Effects of pentoxifylline, 7-nitroindazole, and imipramine on tumor necrosis factor-α and indoleamine 2,3-dioxygenase enzyme activity in the hippocampus and frontal cortex of chronic mild-stress-exposed rats

OBJECTIVES: This study aimed to investigate the role of tumor necrosis factor (TNF)-α and the neuronal nitric oxide synthase enzyme in dysregulation of indoleamine 2,3-dioxygenase (IDO) enzyme, and hence serotonin availability in chronic mild stress (CMS), an animal model of depression. METHODS: Rat...

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Detalles Bibliográficos
Autores principales: Mohamed, Bassim MSA, Aboul-Fotouh, Sawsan, Ibrahim, Eman A, Shehata, Hanan, Mansour, Amal A, Yassin, Nemat AZ, El-Eraky, Wafaa, Abdel-Tawab, Ahmed M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682807/
https://www.ncbi.nlm.nih.gov/pubmed/23785234
http://dx.doi.org/10.2147/NDT.S41020

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