Chronic rhinosinusitis and emerging treatment options

This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corti...

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Autores principales: Piromchai, Patorn, Kasemsiri, Pornthep, Laohasiriwong, Supawan, Thanaviratananich, Sanguansak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682850/
https://www.ncbi.nlm.nih.gov/pubmed/23785241
http://dx.doi.org/10.2147/IJGM.S29977
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author Piromchai, Patorn
Kasemsiri, Pornthep
Laohasiriwong, Supawan
Thanaviratananich, Sanguansak
author_facet Piromchai, Patorn
Kasemsiri, Pornthep
Laohasiriwong, Supawan
Thanaviratananich, Sanguansak
author_sort Piromchai, Patorn
collection PubMed
description This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed.
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spelling pubmed-36828502013-06-19 Chronic rhinosinusitis and emerging treatment options Piromchai, Patorn Kasemsiri, Pornthep Laohasiriwong, Supawan Thanaviratananich, Sanguansak Int J Gen Med Original Research This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed. Dove Medical Press 2013-06-07 /pmc/articles/PMC3682850/ /pubmed/23785241 http://dx.doi.org/10.2147/IJGM.S29977 Text en © 2013 Piromchai et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Piromchai, Patorn
Kasemsiri, Pornthep
Laohasiriwong, Supawan
Thanaviratananich, Sanguansak
Chronic rhinosinusitis and emerging treatment options
title Chronic rhinosinusitis and emerging treatment options
title_full Chronic rhinosinusitis and emerging treatment options
title_fullStr Chronic rhinosinusitis and emerging treatment options
title_full_unstemmed Chronic rhinosinusitis and emerging treatment options
title_short Chronic rhinosinusitis and emerging treatment options
title_sort chronic rhinosinusitis and emerging treatment options
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682850/
https://www.ncbi.nlm.nih.gov/pubmed/23785241
http://dx.doi.org/10.2147/IJGM.S29977
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AT laohasiriwongsupawan chronicrhinosinusitisandemergingtreatmentoptions
AT thanaviratananichsanguansak chronicrhinosinusitisandemergingtreatmentoptions

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