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Expression of ST3GAL4 Leads to SLe(x) Expression and Induces c-Met Activation and an Invasive Phenotype in Gastric Carcinoma Cells
Sialyl-Lewis X (SLe(x)) is a sialylated glycan antigen expressed on the cell surface during malignant cell transformation and is associated with cancer progression and poor prognosis. The increased expression of sialylated glycans is associated with alterations in the expression of sialyltransferase...
Autores principales: | Gomes, Catarina, Osório, Hugo, Pinto, Marta Teixeira, Campos, Diana, Oliveira, Maria José, Reis, Celso A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682978/ https://www.ncbi.nlm.nih.gov/pubmed/23799130 http://dx.doi.org/10.1371/journal.pone.0066737 |
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