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Expression of ST3GAL4 Leads to SLe(x) Expression and Induces c-Met Activation and an Invasive Phenotype in Gastric Carcinoma Cells

Sialyl-Lewis X (SLe(x)) is a sialylated glycan antigen expressed on the cell surface during malignant cell transformation and is associated with cancer progression and poor prognosis. The increased expression of sialylated glycans is associated with alterations in the expression of sialyltransferase...

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Detalles Bibliográficos
Autores principales: Gomes, Catarina, Osório, Hugo, Pinto, Marta Teixeira, Campos, Diana, Oliveira, Maria José, Reis, Celso A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682978/
https://www.ncbi.nlm.nih.gov/pubmed/23799130
http://dx.doi.org/10.1371/journal.pone.0066737

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