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Gene Expression Profiling Specifies Chemokine, Mitochondrial and Lipid Metabolism Signatures in Leprosy

Herein, we performed microarray experiments in Schwann cells infected with live M. leprae and identified novel differentially expressed genes (DEG) in M. leprae infected cells. Also, we selected candidate genes associated or implicated with leprosy in genetic studies and biological experiments. Fort...

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Detalles Bibliográficos
Autores principales: Guerreiro, Luana Tatiana Albuquerque, Robottom-Ferreira, Anna Beatriz, Ribeiro-Alves, Marcelo, Toledo-Pinto, Thiago Gomes, Rosa Brito, Tiana, Rosa, Patrícia Sammarco, Sandoval, Felipe Galvan, Jardim, Márcia Rodrigues, Antunes, Sérgio Gomes, Shannon, Edward J., Sarno, Euzenir Nunes, Pessolani, Maria Cristina Vidal, Williams, Diana Lynn, Moraes, Milton Ozório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683049/
https://www.ncbi.nlm.nih.gov/pubmed/23798993
http://dx.doi.org/10.1371/journal.pone.0064748