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Glial Promoter Selectivity following AAV-Delivery to the Immature Brain

Recombinant adeno-associated virus (AAV) vectors are versatile tools for gene transfer to the central nervous system (CNS) and proof-of-concept studies in adult rodents have shown that the use of cell type-specific promoters is sufficient to target AAV-mediated transgene expression to glia. However,...

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Detalles Bibliográficos
Autores principales: von Jonquieres, Georg, Mersmann, Nadine, Klugmann, Claudia Bettina, Harasta, Anne Editha, Lutz, Beat, Teahan, Orla, Housley, Gary David, Fröhlich, Dominik, Krämer-Albers, Eva-Maria, Klugmann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683058/
https://www.ncbi.nlm.nih.gov/pubmed/23799030
http://dx.doi.org/10.1371/journal.pone.0065646

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