Probucol Increases Striatal Glutathione Peroxidase Activity and Protects against 3-Nitropropionic Acid-Induced Pro-Oxidative Damage in Rats

Huntington’s disease (HD) is an autosomal dominantly inherited neurodegenerative disease characterized by symptoms attributable to the death of striatal and cortical neurons. The molecular mechanisms mediating neuronal death in HD involve oxidative stress and mitochondrial dysfunction. Administratio...

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Detalles Bibliográficos
Autores principales: Colle, Dirleise, Santos, Danúbia Bonfanti, Moreira, Eduardo Luiz Gasnhar, Hartwig, Juliana Montagna, dos Santos, Alessandra Antunes, Zimmermann, Luciana Teixeira, Hort, Mariana Appel, Farina, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683065/
https://www.ncbi.nlm.nih.gov/pubmed/23799154
http://dx.doi.org/10.1371/journal.pone.0067658

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