Cargando…
The Rho-GEF Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2
Inflammation is characterized by endothelium that highly expresses numerous adhesion molecules to trigger leukocyte extravasation. Central to this event is increased gene transcription. Small Rho-GTPases not only control the actin cytoskeleton, but are also implicated in gene regulation. However, in...
Autores principales: | Van Rijssel, Jos, Timmerman, Ilse, Van Alphen, Floris P. J., Hoogenboezem, Mark, Korchynskyi, Olexandr, Geerts, Dirk, Geissler, Judy, Reedquist, Kris A., Niessen, Hans W. M., Van Buul, Jaap D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683159/ https://www.ncbi.nlm.nih.gov/pubmed/23789107 http://dx.doi.org/10.1242/bio.20134382 |
Ejemplares similares
-
The RhoGEF Trio: A Protein with a Wide Range of Functions in the Vascular Endothelium
por: Kempers, Lanette, et al.
Publicado: (2021) -
The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation
por: van Rijssel, Jos, et al.
Publicado: (2012) -
Flow-induced endothelial cell alignment requires the RhoGEF Trio as a scaffold protein to polarize active Rac1 distribution
por: Kroon, Jeffrey, et al.
Publicado: (2017) -
Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions
por: Daniel, Anna E., et al.
Publicado: (2023) -
The many faces of the guanine-nucleotide exchange factor trio
por: van Rijssel, Jos, et al.
Publicado: (2012)