Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis

Neuronal ceroid lipofuscinoses, the most common fatal childhood neurodegenerative illnesses, share many features with more prevalent neurodegenerative diseases. Neuronal ceroid lipofuscinoses are caused by mutations in CLN genes. CLN6 encodes a transmembrane endoplasmic reticulum protein with no kno...

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Detalles Bibliográficos
Autores principales: Kanninen, Katja M., Grubman, Alexandra, Caragounis, Aphrodite, Duncan, Clare, Parker, Sarah J., Lidgerwood, Grace E., Volitakis, Irene, Ganio, George, Crouch, Peter J., White, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683166/
https://www.ncbi.nlm.nih.gov/pubmed/23789114
http://dx.doi.org/10.1242/bio.20134804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683166/
https://www.ncbi.nlm.nih.gov/pubmed/23789114
http://dx.doi.org/10.1242/bio.20134804

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