The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics

The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal te...

Descripción completa

Detalles Bibliográficos
Autores principales: Fellinger, Christina, Wantke, Felix, Hemmer, Wolfgang, Sesztak-Greinecker, Gabriele, Wöhrl, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683437/
https://www.ncbi.nlm.nih.gov/pubmed/23818903
http://dx.doi.org/10.1155/2013/201586
_version_ 1782273495878598656
author Fellinger, Christina
Wantke, Felix
Hemmer, Wolfgang
Sesztak-Greinecker, Gabriele
Wöhrl, Stefan
author_facet Fellinger, Christina
Wantke, Felix
Hemmer, Wolfgang
Sesztak-Greinecker, Gabriele
Wöhrl, Stefan
author_sort Fellinger, Christina
collection PubMed
description The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal testing were done with lidocaine, mepivacaine, and procaine. Intradermal testing showed positive reactions to mepivacaine (1 : 10), undiluted lidocaine, and procaine (1 : 10 and undiluted). Specific IgE could be detected against mepivacaine, but not against latex. Serum tryptase was in the normal range. In order to rule out the exceptional case of a true IgE-mediated reaction, allergy testing with local anaesthetics is still required in the workup of patients.
format Online
Article
Text
id pubmed-3683437
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-36834372013-07-01 The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics Fellinger, Christina Wantke, Felix Hemmer, Wolfgang Sesztak-Greinecker, Gabriele Wöhrl, Stefan Case Rep Med Case Report The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local anaesthetic. Skin prick testing and intradermal testing were done with lidocaine, mepivacaine, and procaine. Intradermal testing showed positive reactions to mepivacaine (1 : 10), undiluted lidocaine, and procaine (1 : 10 and undiluted). Specific IgE could be detected against mepivacaine, but not against latex. Serum tryptase was in the normal range. In order to rule out the exceptional case of a true IgE-mediated reaction, allergy testing with local anaesthetics is still required in the workup of patients. Hindawi Publishing Corporation 2013 2013-05-30 /pmc/articles/PMC3683437/ /pubmed/23818903 http://dx.doi.org/10.1155/2013/201586 Text en Copyright © 2013 Christina Fellinger et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fellinger, Christina
Wantke, Felix
Hemmer, Wolfgang
Sesztak-Greinecker, Gabriele
Wöhrl, Stefan
The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_full The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_fullStr The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_full_unstemmed The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_short The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics
title_sort rare case of a probably true ige-mediated allergy to local anaesthetics
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683437/
https://www.ncbi.nlm.nih.gov/pubmed/23818903
http://dx.doi.org/10.1155/2013/201586
work_keys_str_mv AT fellingerchristina therarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT wantkefelix therarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT hemmerwolfgang therarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT sesztakgreineckergabriele therarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT wohrlstefan therarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT fellingerchristina rarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT wantkefelix rarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT hemmerwolfgang rarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT sesztakgreineckergabriele rarecaseofaprobablytrueigemediatedallergytolocalanaesthetics
AT wohrlstefan rarecaseofaprobablytrueigemediatedallergytolocalanaesthetics

Ejemplares similares