Cargando…
Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects
Descemet membrane endothelial keratoplasty (DMEK) is a corneal surgical technique which selectively replaces the damaged posterior part of the cornea with a healthy donor graft retaining the rest of the tissue intact. There is a need to validate and standardize the donor tissue before grafting due t...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683473/ https://www.ncbi.nlm.nih.gov/pubmed/23819041 http://dx.doi.org/10.1155/2013/769860 |
_version_ | 1782273500987260928 |
---|---|
author | Parekh, Mohit Salvalaio, Gianni Ruzza, Alessandro Camposampiero, Davide Griffoni, Carlo Zampini, Alfonso Ponzin, Diego Ferrari, Stefano |
author_facet | Parekh, Mohit Salvalaio, Gianni Ruzza, Alessandro Camposampiero, Davide Griffoni, Carlo Zampini, Alfonso Ponzin, Diego Ferrari, Stefano |
author_sort | Parekh, Mohit |
collection | PubMed |
description | Descemet membrane endothelial keratoplasty (DMEK) is a corneal surgical technique which selectively replaces the damaged posterior part of the cornea with a healthy donor graft retaining the rest of the tissue intact. There is a need to validate and standardize the donor tissue before grafting due to certain issues that can lead to consequences such as graft failure due to poor endothelial cell count, higher mortality, detachment of the graft, or increased surgical expenses, time, and effort. Thus, prospective potential surgeons and eye banks should now aim at developing new improved surgical techniques in order to prepare the best suited, validated, precut, preloaded, and easy to transplant tissue to reduce pre- and postsurgical complications. This could be achieved by defining parameters like graft thickness, accepted mortality threshold of the endothelial cells, and behavior of grafts during preservation and transportation along with using more sophisticated instruments like microkeratome and femtosecond lasers for graft preparation. Thus, a rapport between the eye banks and the surgeons along with the advanced instruments can overcome this challenge to find the best possible solution for endothelial keratoplasty (EK). |
format | Online Article Text |
id | pubmed-3683473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36834732013-07-01 Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects Parekh, Mohit Salvalaio, Gianni Ruzza, Alessandro Camposampiero, Davide Griffoni, Carlo Zampini, Alfonso Ponzin, Diego Ferrari, Stefano J Ophthalmol Review Article Descemet membrane endothelial keratoplasty (DMEK) is a corneal surgical technique which selectively replaces the damaged posterior part of the cornea with a healthy donor graft retaining the rest of the tissue intact. There is a need to validate and standardize the donor tissue before grafting due to certain issues that can lead to consequences such as graft failure due to poor endothelial cell count, higher mortality, detachment of the graft, or increased surgical expenses, time, and effort. Thus, prospective potential surgeons and eye banks should now aim at developing new improved surgical techniques in order to prepare the best suited, validated, precut, preloaded, and easy to transplant tissue to reduce pre- and postsurgical complications. This could be achieved by defining parameters like graft thickness, accepted mortality threshold of the endothelial cells, and behavior of grafts during preservation and transportation along with using more sophisticated instruments like microkeratome and femtosecond lasers for graft preparation. Thus, a rapport between the eye banks and the surgeons along with the advanced instruments can overcome this challenge to find the best possible solution for endothelial keratoplasty (EK). Hindawi Publishing Corporation 2013 2013-05-30 /pmc/articles/PMC3683473/ /pubmed/23819041 http://dx.doi.org/10.1155/2013/769860 Text en Copyright © 2013 Mohit Parekh et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Parekh, Mohit Salvalaio, Gianni Ruzza, Alessandro Camposampiero, Davide Griffoni, Carlo Zampini, Alfonso Ponzin, Diego Ferrari, Stefano Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects |
title | Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects |
title_full | Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects |
title_fullStr | Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects |
title_full_unstemmed | Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects |
title_short | Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects |
title_sort | posterior lamellar graft preparation: a prospective review from an eye bank on current and future aspects |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683473/ https://www.ncbi.nlm.nih.gov/pubmed/23819041 http://dx.doi.org/10.1155/2013/769860 |
work_keys_str_mv | AT parekhmohit posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT salvalaiogianni posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT ruzzaalessandro posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT camposampierodavide posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT griffonicarlo posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT zampinialfonso posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT ponzindiego posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects AT ferraristefano posteriorlamellargraftpreparationaprospectivereviewfromaneyebankoncurrentandfutureaspects |