Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome

Nucleotide excision repair (NER) removes UV-induced DNA damage and other bulky DNA lesions thereby maintaining genomic integrity. Dr. Qingyi Wei’s group demonstrated over the last decade that NER fidelity and single nucleotide polymorphisms (SNPs) in NER genes constitute melanoma risk biomarkers. In...

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Detalles Bibliográficos
Autores principales: Emmert, Steffen, Kraemer, Kenneth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683875/
https://www.ncbi.nlm.nih.gov/pubmed/23760049
http://dx.doi.org/10.1038/jid.2013.72
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author Emmert, Steffen
Kraemer, Kenneth H.
author_facet Emmert, Steffen
Kraemer, Kenneth H.
author_sort Emmert, Steffen
collection PubMed
description Nucleotide excision repair (NER) removes UV-induced DNA damage and other bulky DNA lesions thereby maintaining genomic integrity. Dr. Qingyi Wei’s group demonstrated over the last decade that NER fidelity and single nucleotide polymorphisms (SNPs) in NER genes constitute melanoma risk biomarkers. In this issue (Li et al.) they provide evidence that SNPs in NER genes may also predict melanoma survival.
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spelling pubmed-36838752014-01-01 Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome Emmert, Steffen Kraemer, Kenneth H. J Invest Dermatol Article Nucleotide excision repair (NER) removes UV-induced DNA damage and other bulky DNA lesions thereby maintaining genomic integrity. Dr. Qingyi Wei’s group demonstrated over the last decade that NER fidelity and single nucleotide polymorphisms (SNPs) in NER genes constitute melanoma risk biomarkers. In this issue (Li et al.) they provide evidence that SNPs in NER genes may also predict melanoma survival. 2013-07 /pmc/articles/PMC3683875/ /pubmed/23760049 http://dx.doi.org/10.1038/jid.2013.72 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Emmert, Steffen
Kraemer, Kenneth H.
Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome
title Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome
title_full Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome
title_fullStr Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome
title_full_unstemmed Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome
title_short Do not underestimate nucleotide excision repair: It not only predicts melanoma risk but also survival outcome
title_sort do not underestimate nucleotide excision repair: it not only predicts melanoma risk but also survival outcome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683875/
https://www.ncbi.nlm.nih.gov/pubmed/23760049
http://dx.doi.org/10.1038/jid.2013.72
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