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The Runt domain of AML1 (RUNX1) binds a sequence-conserved RNA motif that mimics a DNA element

AML1 (RUNX1) is a key transcription factor for hematopoiesis that binds to the Runt-binding double-stranded DNA element (RDE) of target genes through its N-terminal Runt domain. Aberrations in the AML1 gene are frequently found in human leukemia. To better understand AML1 and its potential utility f...

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Detalles Bibliográficos
Autores principales:	Fukunaga, Junichi, Nomura, Yusuke, Tanaka, Yoichiro, Amano, Ryo, Tanaka, Taku, Nakamura, Yoshikazu, Kawai, Gota, Sakamoto, Taiichi, Kozu, Tomoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683927/ https://www.ncbi.nlm.nih.gov/pubmed/23709277 http://dx.doi.org/10.1261/rna.037879.112

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