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Activation of Protease-Activated Receptor 2-Mediated Signaling by Mast Cell Tryptase Modulates Cytokine Production in Primary Cultured Astrocytes

Protease-activated receptor 2 (PAR-2), which is abundantly expressed in astrocytes, is known to play major roles in brain inflammation. However, the influence of the natural agonist of PAR-2, tryptase, on proinflammatory mediator releasedfrom astrocytes remains uninvestigated. In the present study,...

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Detalles Bibliográficos
Autores principales:	Zeng, Xiaoning, Zhang, Shu, Xu, Luwei, Yang, Haiwei, He, Shaoheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684029/ https://www.ncbi.nlm.nih.gov/pubmed/23818741 http://dx.doi.org/10.1155/2013/140812

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