Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells

CD25, the alpha chain of the interleukin-2 receptor, is expressed in activated T cells and plays a significant role in autoimmune disease and tumorigenesis; however, the mechanisms regulating transcription of CD25 remain elusive. Here we identify the Src-associated substrate during mitosis of 68kDa...

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Detalles Bibliográficos
Autores principales: Fu, Kai, Sun, Xin, Zheng, Wenxin, Wier, Eric M., Hodgson, Andrea, Tran, Dat Q., Richard, Stéphane, Wan, Fengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684077/
https://www.ncbi.nlm.nih.gov/pubmed/23715268
http://dx.doi.org/10.1038/ncomms2916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684077/
https://www.ncbi.nlm.nih.gov/pubmed/23715268
http://dx.doi.org/10.1038/ncomms2916

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