TET2 promotes histone O-GlcNAcylation during gene transcription

TET enzymes including TET1, 2 and 3 convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC)(1) and regulate gene transcription(2-5). However, this molecular mechanism by which TET family enzymes regulate gene transcription remains elusive(5-6). Here, using protein affinity purification, we...

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Detalles Bibliográficos
Autores principales: Chen, Qiang, Chen, Yibin, Bian, Chunjing, Fujiki, Ryoji, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684361/
https://www.ncbi.nlm.nih.gov/pubmed/23222540
http://dx.doi.org/10.1038/nature11742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684361/
https://www.ncbi.nlm.nih.gov/pubmed/23222540
http://dx.doi.org/10.1038/nature11742

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