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TET2 promotes histone O-GlcNAcylation during gene transcription
TET enzymes including TET1, 2 and 3 convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC)(1) and regulate gene transcription(2-5). However, this molecular mechanism by which TET family enzymes regulate gene transcription remains elusive(5-6). Here, using protein affinity purification, we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684361/ https://www.ncbi.nlm.nih.gov/pubmed/23222540 http://dx.doi.org/10.1038/nature11742 |