Gender difference in QTc prolongation of people with mental disorders

BACKGROUND: We examined gender difference in QTc interval distribution and its related factors in people with mental disorders. METHODS: We retrospectively reviewed medical charts of patients discharged from a university psychiatric unit between November 1997 and December 2000. Subjects were 328 pat...

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Detalles Bibliográficos
Autores principales: Ito, Hiroto, Kono, Toshiaki, Ishida, Shigenobu, Maeda, Hisao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368443/
https://www.ncbi.nlm.nih.gov/pubmed/14965357
http://dx.doi.org/10.1186/1475-2832-3-3
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author Ito, Hiroto
Kono, Toshiaki
Ishida, Shigenobu
Maeda, Hisao
author_facet Ito, Hiroto
Kono, Toshiaki
Ishida, Shigenobu
Maeda, Hisao
author_sort Ito, Hiroto
collection PubMed
description BACKGROUND: We examined gender difference in QTc interval distribution and its related factors in people with mental disorders. METHODS: We retrospectively reviewed medical charts of patients discharged from a university psychiatric unit between November 1997 and December 2000. Subjects were 328 patients (145 males and 183 females) taking psychotropics at their admission. We examined patient characteristics, medical history, diagnosis, and medication before admission. RESULTS: Mean QTc interval was 0.408 (SD = 0.036). QTc intervals in females were significantly longer than those in males. QTc of females without comorbidity was significantly longer than that of males. CONCLUSION: The influence of gender difference on QTc prolongation in people with mental disorders merits further research.
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spelling pubmed-3684432004-03-14 Gender difference in QTc prolongation of people with mental disorders Ito, Hiroto Kono, Toshiaki Ishida, Shigenobu Maeda, Hisao Ann Gen Hosp Psychiatry Primary Research BACKGROUND: We examined gender difference in QTc interval distribution and its related factors in people with mental disorders. METHODS: We retrospectively reviewed medical charts of patients discharged from a university psychiatric unit between November 1997 and December 2000. Subjects were 328 patients (145 males and 183 females) taking psychotropics at their admission. We examined patient characteristics, medical history, diagnosis, and medication before admission. RESULTS: Mean QTc interval was 0.408 (SD = 0.036). QTc intervals in females were significantly longer than those in males. QTc of females without comorbidity was significantly longer than that of males. CONCLUSION: The influence of gender difference on QTc prolongation in people with mental disorders merits further research. BioMed Central 2004-02-13 /pmc/articles/PMC368443/ /pubmed/14965357 http://dx.doi.org/10.1186/1475-2832-3-3 Text en Copyright © 2004 Ito et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
spellingShingle Primary Research
Ito, Hiroto
Kono, Toshiaki
Ishida, Shigenobu
Maeda, Hisao
Gender difference in QTc prolongation of people with mental disorders
title Gender difference in QTc prolongation of people with mental disorders
title_full Gender difference in QTc prolongation of people with mental disorders
title_fullStr Gender difference in QTc prolongation of people with mental disorders
title_full_unstemmed Gender difference in QTc prolongation of people with mental disorders
title_short Gender difference in QTc prolongation of people with mental disorders
title_sort gender difference in qtc prolongation of people with mental disorders
topic Primary Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368443/
https://www.ncbi.nlm.nih.gov/pubmed/14965357
http://dx.doi.org/10.1186/1475-2832-3-3
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AT ishidashigenobu genderdifferenceinqtcprolongationofpeoplewithmentaldisorders
AT maedahisao genderdifferenceinqtcprolongationofpeoplewithmentaldisorders

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