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Combining mTOR Inhibition with Radiation Improves Antitumor Activity in Bladder Cancer Cells In Vitro and In Vivo: A Novel Strategy for Treatment

PURPOSE: Radiation therapy for invasive bladder cancer allows for organ preservation but toxicity and local control remain problematic. As such, improving efficacy of treatment requires radiosensitization of tumor cells. The aim of study is to investigate if the mammalian Target of Rapamycin (mTOR),...

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Detalles Bibliográficos
Autores principales: Nassim, Roland, Mansure, Jose Joao, Chevalier, Simone, Cury, Fabio, Kassouf, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684614/
https://www.ncbi.nlm.nih.gov/pubmed/23799002
http://dx.doi.org/10.1371/journal.pone.0065257