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Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia
BACKGROUND: Cancer cachexia is a severe wasting syndrome characterized by the progressive loss of lean body mass and systemic inflammation. Inhibiting the signaling of the transcription factor nuclear factor kappa B (NF-κB) largely prevents cancer-induced muscle wasting in murine models. We have pre...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684703/ https://www.ncbi.nlm.nih.gov/pubmed/23344889 http://dx.doi.org/10.1007/s13539-012-0101-7 |