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Methyl 5′′-chloro-1′,1′′-dimethyl-2,2′′-dioxodispiro[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carboxylate
In the title compound, C(22)H(20)ClN(3)O(4), the central pyrrolidine ring adopts an envelope conformation on the N atom. The indolinone systems are individually roughly planar, with maximum deviations from their mean planes of 0.130 Å for the spiro C atom of the indolinone unit and 0.172 Å for the c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684914/ https://www.ncbi.nlm.nih.gov/pubmed/23795016 http://dx.doi.org/10.1107/S1600536813011501 |
Sumario: | In the title compound, C(22)H(20)ClN(3)O(4), the central pyrrolidine ring adopts an envelope conformation on the N atom. The indolinone systems are individually roughly planar, with maximum deviations from their mean planes of 0.130 Å for the spiro C atom of the indolinone unit and 0.172 Å for the carbonyl C atom of the 5-chloro-1-methylindolinone unit. They make dihedral angles of 77.7 (8) and 86.1 (8)° with the mean plane through the central pyrrolidine ring. In the crystal, molecules are linked by N—H⋯O hydrogen bonds supported by C—H⋯O contacts into chains along the ab diagonal. The structure also features C—H⋯O hydrogen bonds, forming R (2) (2)(8) and R (2) (2)(16) rings and generating a three-dimensional array. |
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