N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide

The fused pyrazole and pyrimidine rings in the title compound, C(22)H(19)BrN(4)O, are almost coplanar, their planes being inclined to one another by 2.08 (13)°. The dihedral angles formed by the mean plane of the fused ring system and the phenyl and benzene rings are 16.21 (4) and 82.84 (4)°, respec...

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Autores principales: Bassoude, Ibtissam, Berteina-Raboin, Sabine, Essassi, El Mokhtar, Guillaumet, Gérald, El Ammari, Lahcen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684917/
https://www.ncbi.nlm.nih.gov/pubmed/23795019
http://dx.doi.org/10.1107/S1600536813011811
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author Bassoude, Ibtissam
Berteina-Raboin, Sabine
Essassi, El Mokhtar
Guillaumet, Gérald
El Ammari, Lahcen
author_facet Bassoude, Ibtissam
Berteina-Raboin, Sabine
Essassi, El Mokhtar
Guillaumet, Gérald
El Ammari, Lahcen
author_sort Bassoude, Ibtissam
collection PubMed
description The fused pyrazole and pyrimidine rings in the title compound, C(22)H(19)BrN(4)O, are almost coplanar, their planes being inclined to one another by 2.08 (13)°. The dihedral angles formed by the mean plane of the fused ring system and the phenyl and benzene rings are 16.21 (4) and 82.84 (4)°, respectively. An intra­molecular N—H⋯N hydrogen bond is observed. In the crystal, mol­ecules form inversion dimers via pairs of C—H⋯O hydrogen bonds. π–π inter­actions, with centroid–centroid distances of 3.4916 (9) Å, connect the dimers into a three-dimensional network.
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spelling pubmed-36849172013-06-21 N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide Bassoude, Ibtissam Berteina-Raboin, Sabine Essassi, El Mokhtar Guillaumet, Gérald El Ammari, Lahcen Acta Crystallogr Sect E Struct Rep Online Organic Papers The fused pyrazole and pyrimidine rings in the title compound, C(22)H(19)BrN(4)O, are almost coplanar, their planes being inclined to one another by 2.08 (13)°. The dihedral angles formed by the mean plane of the fused ring system and the phenyl and benzene rings are 16.21 (4) and 82.84 (4)°, respectively. An intra­molecular N—H⋯N hydrogen bond is observed. In the crystal, mol­ecules form inversion dimers via pairs of C—H⋯O hydrogen bonds. π–π inter­actions, with centroid–centroid distances of 3.4916 (9) Å, connect the dimers into a three-dimensional network. International Union of Crystallography 2013-05-04 /pmc/articles/PMC3684917/ /pubmed/23795019 http://dx.doi.org/10.1107/S1600536813011811 Text en © Bassoude et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Bassoude, Ibtissam
Berteina-Raboin, Sabine
Essassi, El Mokhtar
Guillaumet, Gérald
El Ammari, Lahcen
N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
title N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
title_full N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
title_fullStr N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
title_full_unstemmed N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
title_short N-(2-Bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
title_sort n-(2-bromo-4-methyl­phen­yl)-2-(5-methyl-2-phenyl­pyrazolo­[1,5-a]pyrimidin-7-yl)acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684917/
https://www.ncbi.nlm.nih.gov/pubmed/23795019
http://dx.doi.org/10.1107/S1600536813011811
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