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Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate

The title compound, C(32)H(28)Cl(2)N(2)O(2), was synthesized by a multicomponent reaction of 4-chloro­benzaldehyde, aniline and ethyl aceto­acetate. The central 1,2,5,6-tetra­hydro­pyridine ring exhibits a distorted boat conformation and the two chloro­phenyl rings attached to the central ring at po...

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Detalles Bibliográficos
Autores principales: Yu, Jianfeng, Tang, Shiming, Zeng, Jingbin, Yan, Zifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685090/
https://www.ncbi.nlm.nih.gov/pubmed/23795109
http://dx.doi.org/10.1107/S1600536813013573
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author Yu, Jianfeng
Tang, Shiming
Zeng, Jingbin
Yan, Zifeng
author_facet Yu, Jianfeng
Tang, Shiming
Zeng, Jingbin
Yan, Zifeng
author_sort Yu, Jianfeng
collection PubMed
description The title compound, C(32)H(28)Cl(2)N(2)O(2), was synthesized by a multicomponent reaction of 4-chloro­benzaldehyde, aniline and ethyl aceto­acetate. The central 1,2,5,6-tetra­hydro­pyridine ring exhibits a distorted boat conformation and the two chloro­phenyl rings attached to the central ring at positions 2 and 6 are oriented in opposite directions. The two O atoms of the eth­oxy­carbonyl group are involved in intra­molecular N—H⋯O and C—H⋯O hydrogen bonds. In the crystal, weak C—H⋯O hydrogen bonds link mol­ecules related by translation along the b axis into chains.
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spelling pubmed-36850902013-06-21 Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate Yu, Jianfeng Tang, Shiming Zeng, Jingbin Yan, Zifeng Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(32)H(28)Cl(2)N(2)O(2), was synthesized by a multicomponent reaction of 4-chloro­benzaldehyde, aniline and ethyl aceto­acetate. The central 1,2,5,6-tetra­hydro­pyridine ring exhibits a distorted boat conformation and the two chloro­phenyl rings attached to the central ring at positions 2 and 6 are oriented in opposite directions. The two O atoms of the eth­oxy­carbonyl group are involved in intra­molecular N—H⋯O and C—H⋯O hydrogen bonds. In the crystal, weak C—H⋯O hydrogen bonds link mol­ecules related by translation along the b axis into chains. International Union of Crystallography 2013-05-22 /pmc/articles/PMC3685090/ /pubmed/23795109 http://dx.doi.org/10.1107/S1600536813013573 Text en © Yu et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yu, Jianfeng
Tang, Shiming
Zeng, Jingbin
Yan, Zifeng
Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_full Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_fullStr Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_full_unstemmed Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_short Ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
title_sort ethyl 4-anilino-2,6-bis­(4-chloro­phen­yl)-1-phenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685090/
https://www.ncbi.nlm.nih.gov/pubmed/23795109
http://dx.doi.org/10.1107/S1600536813013573
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