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Rupatadine
In the title compound (systematic name: 8-chloro-11-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine), C(26)H(26)ClN(3), the dihedral angle between the mean planes of the chlorophenyl and cyclohepta[1,2-b]pyridinyl rings fused to the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685114/ https://www.ncbi.nlm.nih.gov/pubmed/23795133 http://dx.doi.org/10.1107/S1600536813014256 |
Sumario: | In the title compound (systematic name: 8-chloro-11-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine), C(26)H(26)ClN(3), the dihedral angle between the mean planes of the chlorophenyl and cyclohepta[1,2-b]pyridinyl rings fused to the cycloheptane ring is 56.6 (1)°. The mean planes of the cyclohepta[1,2-b]pyridinyl and 5-methylpyridin-3-yl rings are twisted by 64.9 (4)°. The central piperizene group is in a slightly distorted chair configuration. A weak intramolecular C—H⋯N interaction is observed between the cyclohepta[1,2-b]pyridinyl and piperidin-4-ylidene moieties. |
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