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Anti-VEGF agents in metastatic colorectal cancer (mCRC): are they all alike?

Bevacizumab is a monoclonal antibody that binds and neutralizes vascular endothelial growth factor (VEGF)-A, a key player in the angiogenesis pathway. Despite benefits of bevacizumab in cancer therapy, it is clear that the VEGF pathway is complex, involving multiple isoforms, receptors, and alternat...

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Detalles Bibliográficos
Autor principal:	Saif, Muhammad Wasif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685399/ https://www.ncbi.nlm.nih.gov/pubmed/23807861 http://dx.doi.org/10.2147/CMAR.S45193

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