Cargando…
Approaches to the detection of recessive effects using next generation sequencing data from outbred populations
Conventional methods to analyze genome-wide association studies and whole exome or whole genome sequencing studies would be prone to overlook variants which might exert a recessive effect on risk of disease, either as homozygotes or compound heterozygotes. It is plausible that such effects may be co...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685401/ https://www.ncbi.nlm.nih.gov/pubmed/23807854 http://dx.doi.org/10.2147/AABC.S44332 |