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Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study

Objectives To test the hypothesis that low risk women at the onset of labour with planned home birth have a higher rate of severe acute maternal morbidity than women with planned hospital birth, and to compare the rate of postpartum haemorrhage and manual removal of placenta. Design Cohort study usi...

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Autores principales: de Jonge, Ank, Mesman, Jeanette A J M, Manniën, Judith, Zwart, Joost J, van Dillen, Jeroen, van Roosmalen, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685517/
https://www.ncbi.nlm.nih.gov/pubmed/23766482
http://dx.doi.org/10.1136/bmj.f3263
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author de Jonge, Ank
Mesman, Jeanette A J M
Manniën, Judith
Zwart, Joost J
van Dillen, Jeroen
van Roosmalen, Jos
author_facet de Jonge, Ank
Mesman, Jeanette A J M
Manniën, Judith
Zwart, Joost J
van Dillen, Jeroen
van Roosmalen, Jos
author_sort de Jonge, Ank
collection PubMed
description Objectives To test the hypothesis that low risk women at the onset of labour with planned home birth have a higher rate of severe acute maternal morbidity than women with planned hospital birth, and to compare the rate of postpartum haemorrhage and manual removal of placenta. Design Cohort study using a linked dataset. Setting Information on all cases of severe acute maternal morbidity in the Netherlands collected by the national study into ethnic determinants of maternal morbidity in the netherlands (LEMMoN study), 1 August 2004 to 1 August 2006, merged with data from the Netherlands perinatal register of all births occurring during the same period. Participants 146 752 low risk women in primary care at the onset of labour. Main outcome measures Severe acute maternal morbidity (admission to an intensive care unit, eclampsia, blood transfusion of four or more packed cells, and other serious events), postpartum haemorrhage, and manual removal of placenta. Results Overall, 92 333 (62.9%) women had a planned home birth and 54 419 (37.1%) a planned hospital birth. The rate of severe acute maternal morbidity among planned primary care births was 2.0 per 1000 births. For nulliparous women the rate for planned home versus planned hospital birth was 2.3 versus 3.1 per 1000 births (adjusted odds ratio 0.77, 95% confidence interval 0.56 to 1.06), relative risk reduction 25.7% (95% confidence interval −0.1% to 53.5%), the rate of postpartum haemorrhage was 43.1 versus 43.3 (0.92, 0.85 to 1.00 and 0.5%, −6.8% to 7.9%), and the rate of manual removal of placenta was 29.0 versus 29.8 (0.91, 0.83 to 1.00 and 2.8%, −6.1% to 11.8%). For parous women the rate of severe acute maternal morbidity for planned home versus planned hospital birth was 1.0 versus 2.3 per 1000 births (0.43, 0.29 to 0.63 and 58.3%, 33.2% to 87.5%), the rate of postpartum haemorrhage was 19.6 versus 37.6 (0.50, 0.46 to 0.55 and 47.9%, 41.2% to 54.7%), and the rate of manual removal of placenta was 8.5 versus 19.6 (0.41, 0.36 to 0.47 and 56.9%, 47.9% to 66.3%). Conclusions Low risk women in primary care at the onset of labour with planned home birth had lower rates of severe acute maternal morbidity, postpartum haemorrhage, and manual removal of placenta than those with planned hospital birth. For parous women these differences were statistically significant. Absolute risks were small in both groups. There was no evidence that planned home birth among low risk women leads to an increased risk of severe adverse maternal outcomes in a maternity care system with well trained midwives and a good referral and transportation system.
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spelling pubmed-36855172013-06-20 Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study de Jonge, Ank Mesman, Jeanette A J M Manniën, Judith Zwart, Joost J van Dillen, Jeroen van Roosmalen, Jos BMJ Research Objectives To test the hypothesis that low risk women at the onset of labour with planned home birth have a higher rate of severe acute maternal morbidity than women with planned hospital birth, and to compare the rate of postpartum haemorrhage and manual removal of placenta. Design Cohort study using a linked dataset. Setting Information on all cases of severe acute maternal morbidity in the Netherlands collected by the national study into ethnic determinants of maternal morbidity in the netherlands (LEMMoN study), 1 August 2004 to 1 August 2006, merged with data from the Netherlands perinatal register of all births occurring during the same period. Participants 146 752 low risk women in primary care at the onset of labour. Main outcome measures Severe acute maternal morbidity (admission to an intensive care unit, eclampsia, blood transfusion of four or more packed cells, and other serious events), postpartum haemorrhage, and manual removal of placenta. Results Overall, 92 333 (62.9%) women had a planned home birth and 54 419 (37.1%) a planned hospital birth. The rate of severe acute maternal morbidity among planned primary care births was 2.0 per 1000 births. For nulliparous women the rate for planned home versus planned hospital birth was 2.3 versus 3.1 per 1000 births (adjusted odds ratio 0.77, 95% confidence interval 0.56 to 1.06), relative risk reduction 25.7% (95% confidence interval −0.1% to 53.5%), the rate of postpartum haemorrhage was 43.1 versus 43.3 (0.92, 0.85 to 1.00 and 0.5%, −6.8% to 7.9%), and the rate of manual removal of placenta was 29.0 versus 29.8 (0.91, 0.83 to 1.00 and 2.8%, −6.1% to 11.8%). For parous women the rate of severe acute maternal morbidity for planned home versus planned hospital birth was 1.0 versus 2.3 per 1000 births (0.43, 0.29 to 0.63 and 58.3%, 33.2% to 87.5%), the rate of postpartum haemorrhage was 19.6 versus 37.6 (0.50, 0.46 to 0.55 and 47.9%, 41.2% to 54.7%), and the rate of manual removal of placenta was 8.5 versus 19.6 (0.41, 0.36 to 0.47 and 56.9%, 47.9% to 66.3%). Conclusions Low risk women in primary care at the onset of labour with planned home birth had lower rates of severe acute maternal morbidity, postpartum haemorrhage, and manual removal of placenta than those with planned hospital birth. For parous women these differences were statistically significant. Absolute risks were small in both groups. There was no evidence that planned home birth among low risk women leads to an increased risk of severe adverse maternal outcomes in a maternity care system with well trained midwives and a good referral and transportation system. BMJ Publishing Group Ltd. 2013-06-13 /pmc/articles/PMC3685517/ /pubmed/23766482 http://dx.doi.org/10.1136/bmj.f3263 Text en © de Jonge et al 2013 http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/.
spellingShingle Research
de Jonge, Ank
Mesman, Jeanette A J M
Manniën, Judith
Zwart, Joost J
van Dillen, Jeroen
van Roosmalen, Jos
Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study
title Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study
title_full Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study
title_fullStr Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study
title_full_unstemmed Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study
title_short Severe adverse maternal outcomes among low risk women with planned home versus hospital births in the Netherlands: nationwide cohort study
title_sort severe adverse maternal outcomes among low risk women with planned home versus hospital births in the netherlands: nationwide cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685517/
https://www.ncbi.nlm.nih.gov/pubmed/23766482
http://dx.doi.org/10.1136/bmj.f3263
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