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Intranasal immunization with a helper-dependent adenoviral vector expressing the codon-optimized fusion glycoprotein of human respiratory syncytial virus elicits protective immunity in BALB/c mice

BACKGROUND: Human respiratory syncytial virus (RSV) is a serious pediatric pathogen of the lower respiratory tract. Currently, there is no clinically approved vaccine against RSV infection. Recent studies have shown that helper-dependent adenoviral (HDAd) vectors may represent effective and safe vac...

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Detalles Bibliográficos
Autores principales:	Fu, Yuan-Hui, He, Jin-Sheng, Qiao, Wei, Jiao, Yue-Ying, Hua, Ying, Zhang, Ying, Peng, Xiang-Lei, Hong, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685604/ https://www.ncbi.nlm.nih.gov/pubmed/23742026 http://dx.doi.org/10.1186/1743-422X-10-183

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