Simultaneous renal clear cell carcinoma and gastrointestinal stromal tumor in one case

Renal cell carcinoma is a tumor in kidney, while gastrointestinal stromal tumors are localized in the stomach and small intestine. They seldom occur simultaneously in sporadic case, both of which were suspective to sunitinib, a tyrosine kinases (RTKs) inhibitor. Our current case is novel in that con...

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Detalles Bibliográficos
Autores principales: Wen, Jin, Li, Han-Zhong, Ji, Zhi Gang, Gang-Yan, Wei, Shi, Bing Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685743/
https://www.ncbi.nlm.nih.gov/pubmed/23798873
http://dx.doi.org/10.4103/0974-7796.110013
Descripción
Sumario:Renal cell carcinoma is a tumor in kidney, while gastrointestinal stromal tumors are localized in the stomach and small intestine. They seldom occur simultaneously in sporadic case, both of which were suspective to sunitinib, a tyrosine kinases (RTKs) inhibitor. Our current case is novel in that concurrent RTK-related tumors are involved in one case. One possible explanation is the presence of some activating mutations.

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