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Epigenetic Therapy in Lung Cancer – Role of microRNAs
Lung cancer is the leading cause of cancer deaths worldwide. microRNAs (miRNAs) are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis, and stem cell main...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685817/ https://www.ncbi.nlm.nih.gov/pubmed/23802096 http://dx.doi.org/10.3389/fonc.2013.00158 |
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author | Rothschild, Sacha I. |
author_facet | Rothschild, Sacha I. |
author_sort | Rothschild, Sacha I. |
collection | PubMed |
description | Lung cancer is the leading cause of cancer deaths worldwide. microRNAs (miRNAs) are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis, and stem cell maintenance. Some miRNAs have been categorized as “oncomiRs” as opposed to “tumor suppressor miRs.” This review focuses on the role of miRNAs in the lung cancer carcinogenesis and their potential as diagnostic, prognostic, or predictive markers. |
format | Online Article Text |
id | pubmed-3685817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-36858172013-06-25 Epigenetic Therapy in Lung Cancer – Role of microRNAs Rothschild, Sacha I. Front Oncol Oncology Lung cancer is the leading cause of cancer deaths worldwide. microRNAs (miRNAs) are a class of small non-coding RNA species that have been implicated in the control of many fundamental cellular and physiological processes such as cellular differentiation, proliferation, apoptosis, and stem cell maintenance. Some miRNAs have been categorized as “oncomiRs” as opposed to “tumor suppressor miRs.” This review focuses on the role of miRNAs in the lung cancer carcinogenesis and their potential as diagnostic, prognostic, or predictive markers. Frontiers Media S.A. 2013-06-19 /pmc/articles/PMC3685817/ /pubmed/23802096 http://dx.doi.org/10.3389/fonc.2013.00158 Text en Copyright © 2013 Rothschild. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. |
spellingShingle | Oncology Rothschild, Sacha I. Epigenetic Therapy in Lung Cancer – Role of microRNAs |
title | Epigenetic Therapy in Lung Cancer – Role of microRNAs |
title_full | Epigenetic Therapy in Lung Cancer – Role of microRNAs |
title_fullStr | Epigenetic Therapy in Lung Cancer – Role of microRNAs |
title_full_unstemmed | Epigenetic Therapy in Lung Cancer – Role of microRNAs |
title_short | Epigenetic Therapy in Lung Cancer – Role of microRNAs |
title_sort | epigenetic therapy in lung cancer – role of micrornas |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685817/ https://www.ncbi.nlm.nih.gov/pubmed/23802096 http://dx.doi.org/10.3389/fonc.2013.00158 |
work_keys_str_mv | AT rothschildsachai epigenetictherapyinlungcancerroleofmicrornas |