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The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination

Although RAD52 plays a critical role in the initiation of homologous recombination (HR) by facilitating the replacement of RPA with RAD51, the mechanism controlling RAD52 remains elusive. Here, we show that Bag101, a factor implicated in proteasome functioning, regulates RAD52 protein levels and sub...

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Detalles Bibliográficos
Autores principales: Saito, Yuichiro, Takeda, Jun, Okada, Masahiro, Kobayashi, Junya, Kato, Akihiro, Hirota, Kouji, Taoka, Masato, Matsumoto, Tomohiro, Komatsu, Kenshi, Isobe, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685826/
https://www.ncbi.nlm.nih.gov/pubmed/23779158
http://dx.doi.org/10.1038/srep02022