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Epitope Mapping of Metuximab on CD147 Using Phage Display and Molecular Docking

Metuximab is the generic name of Licartin, a new drug for radioimmunotherapy of hepatocellular carcinoma. Although it is known to be a mouse monoclonal antibody against CD147, the complete epitope mediating the binding of metuximab to CD147 remains unknown. We panned the Ph.D.-12 phage display pepti...

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Detalles Bibliográficos
Autores principales:	He, Bifang, Mao, Canquan, Ru, Beibei, Han, Hesong, Zhou, Peng, Huang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686076/ https://www.ncbi.nlm.nih.gov/pubmed/23861727 http://dx.doi.org/10.1155/2013/983829

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