Efficient In Vivo Genome Editing Using RNA-Guided Nucleases

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems have evolved in bacteria and archaea as a defense mechanism to silence foreign nucleic acids of viruses and plasmids. Recent work has shown that bacterial type II CRISPR systems can be adapted to creat...

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Detalles Bibliográficos
Autores principales: Hwang, Woong Y., Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L., Tsai, Shengdar Q., Sander, Jeffry D., Peterson, Randall T., Yeh, J.-R. Joanna, Joung, J. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686313/
https://www.ncbi.nlm.nih.gov/pubmed/23360964
http://dx.doi.org/10.1038/nbt.2501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686313/
https://www.ncbi.nlm.nih.gov/pubmed/23360964
http://dx.doi.org/10.1038/nbt.2501

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