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Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death

BACKGROUND: Recent research has revealed that targeting mitochondrial bioenergetic metabolism is a promising chemotherapeutic strategy. Key to successful implementation of this chemotherapeutic strategy is the use of new and improved mitochondria-targeted cationic agents that selectively inhibit ene...

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Detalles Bibliográficos
Autores principales: Cheng, Gang, Zielonka, Jacek, McAllister, Donna M, Mackinnon, A Craig, Joseph, Joy, Dwinell, Michael B, Kalyanaraman, Balaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686663/
https://www.ncbi.nlm.nih.gov/pubmed/23764021
http://dx.doi.org/10.1186/1471-2407-13-285