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Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death
BACKGROUND: Recent research has revealed that targeting mitochondrial bioenergetic metabolism is a promising chemotherapeutic strategy. Key to successful implementation of this chemotherapeutic strategy is the use of new and improved mitochondria-targeted cationic agents that selectively inhibit ene...
Autores principales: | Cheng, Gang, Zielonka, Jacek, McAllister, Donna M, Mackinnon, A Craig, Joseph, Joy, Dwinell, Michael B, Kalyanaraman, Balaraman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686663/ https://www.ncbi.nlm.nih.gov/pubmed/23764021 http://dx.doi.org/10.1186/1471-2407-13-285 |
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