Cargando…
Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice
BACKGROUND: High mobility group box-1 (HMGB1) is a DNA-binding protein that is released from injured cells during inflammation. Advances in targeting HMGB1 represent a major challenge to improve the treatment of acute/chronic inflammation. AIM: This study is aimed at verifying whether the inhibition...
Autores principales: | Vitali, Roberta, Palone, Francesca, Cucchiara, Salvatore, Negroni, Anna, Cavone, Leonardo, Costanzo, Manuela, Aloi, Marina, Dilillo, Anna, Stronati, Laura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686690/ https://www.ncbi.nlm.nih.gov/pubmed/23840500 http://dx.doi.org/10.1371/journal.pone.0066527 |
Ejemplares similares
-
Dipotassium Glycyrrhizate Improves Intestinal Mucosal Healing by Modulating Extracellular Matrix Remodeling Genes and Restoring Epithelial Barrier Functions
por: Stronati, Laura, et al.
Publicado: (2019) -
PARP1 Activation Induces HMGB1 Secretion Promoting Intestinal Inflammation in Mice and Human Intestinal Organoids
por: Vitali, Roberta, et al.
Publicado: (2023) -
Transcription Factor ZNF281: A Novel Player in Intestinal Inflammation and Fibrosis
por: Pierdomenico, Maria, et al.
Publicado: (2018) -
ZNF281 Promotes Colon Fibroblast Activation in TGFβ1-Induced Gut Fibrosis
por: Laudadio, Ilaria, et al.
Publicado: (2022) -
Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal
Homeostasis
por: Negroni, Anna, et al.
Publicado: (2015)