Distinct Roles for CXCR6(+) and CXCR6(−) CD4(+) T Cells in the Pathogenesis of Chronic Colitis

CD4(+) T cells play a central role in the development of inflammatory bowel disease (IBD) via high-level production of effector cytokines such as IFN-γ and TNF-α. To better characterize the colitogenic CD4(+) T cells, we examined their expression of CXCR6, a chemokine receptor that is expressed by T...

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Detalles Bibliográficos
Autores principales: Mandai, Yasushi, Takahashi, Daisuke, Hase, Koji, Obata, Yuuki, Furusawa, Yukihiro, Ebisawa, Masashi, Nakagawa, Tomoo, Sato, Toru, Katsuno, Tatsuro, Saito, Yasushi, Shimaoka, Takeshi, Yokosuka, Osamu, Yokote, Kotaro, Ohno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686755/
https://www.ncbi.nlm.nih.gov/pubmed/23840334
http://dx.doi.org/10.1371/journal.pone.0065488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686755/
https://www.ncbi.nlm.nih.gov/pubmed/23840334
http://dx.doi.org/10.1371/journal.pone.0065488

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