Cargando…
The autoregulation of a eukaryotic DNA transposon
How do DNA transposons live in harmony with their hosts? Bacteria provide the only documented mechanisms for autoregulation, but these are incompatible with eukaryotic cell biology. Here we show that autoregulation of Hsmar1 operates during assembly of the transpososome and arises from the multimeri...
Autores principales: | Claeys Bouuaert, Corentin, Lipkow, Karen, Andrews, Steven S, Liu, Danxu, Chalmers, Ronald |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687335/ https://www.ncbi.nlm.nih.gov/pubmed/23795293 http://dx.doi.org/10.7554/eLife.00668 |
Ejemplares similares
-
Crosstalk between transposase subunits during cleavage of the mariner transposon
por: Claeys Bouuaert, Corentin, et al.
Publicado: (2014) -
Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target
por: Claeys Bouuaert, Corentin, et al.
Publicado: (2013) -
Transposition of the human Hsmar1 transposon: rate-limiting steps and the importance of the flanking TA dinucleotide in second strand cleavage
por: Claeys Bouuaert, Corentin, et al.
Publicado: (2010) -
A single active site in the mariner transposase cleaves DNA strands of opposite polarity
por: Claeys Bouuaert, Corentin, et al.
Publicado: (2017) -
Hyperactive mariner transposons are created by mutations that disrupt allosterism and increase the rate of transposon end synapsis
por: Liu, Danxu, et al.
Publicado: (2014)