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Bilateral Leydig cell tumor of the testis: a case report

Leydig cell tumors are rare testicular tumors of the male gonadal interstitium. Although uncommon, Leydig cell testicular neoplasms are the most common sex cord-stromal tumors and comprise 1–3% of all testicular neoplasms. This tumor is always benign in children and approximately 90% are benign in a...

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Autores principales: Sönmez, Nurettin, Ton, Özlem, Arısan, Serdar, Kılınç, Fatih, Eken, Kamile, Güney, Soner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687425/
https://www.ncbi.nlm.nih.gov/pubmed/23788910
http://dx.doi.org/10.5114/wo.2012.30069
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author Sönmez, Nurettin
Ton, Özlem
Arısan, Serdar
Kılınç, Fatih
Eken, Kamile
Güney, Soner
author_facet Sönmez, Nurettin
Ton, Özlem
Arısan, Serdar
Kılınç, Fatih
Eken, Kamile
Güney, Soner
author_sort Sönmez, Nurettin
collection PubMed
description Leydig cell tumors are rare testicular tumors of the male gonadal interstitium. Although uncommon, Leydig cell testicular neoplasms are the most common sex cord-stromal tumors and comprise 1–3% of all testicular neoplasms. This tumor is always benign in children and approximately 90% are benign in adults. In most cases, patients present with an incidental finding of a testicular mass on scrotal ultrasonography during evaluation of hydroceles or varicoceles or during diagnostic workup for infertility. Leydig cell tumors have been primarily managed with radical inguinal orchiectomy. However, conservative management with testis-sparing surgery in younger adults and children were reported in the literature. Here we report a case of bilateral Leydig cell tumor of the testis treated with radical orchiectomy who presented with the complaint of infertilityand no disease recurrence in followup for 9 months. The patient is currently disease-free and under androgen supplemantation for androgen insufficiency. We recommend complete exam and diagnostic workup in patients with infertility and azoospermia.
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spelling pubmed-36874252013-06-20 Bilateral Leydig cell tumor of the testis: a case report Sönmez, Nurettin Ton, Özlem Arısan, Serdar Kılınç, Fatih Eken, Kamile Güney, Soner Contemp Oncol (Pozn) Case Report Leydig cell tumors are rare testicular tumors of the male gonadal interstitium. Although uncommon, Leydig cell testicular neoplasms are the most common sex cord-stromal tumors and comprise 1–3% of all testicular neoplasms. This tumor is always benign in children and approximately 90% are benign in adults. In most cases, patients present with an incidental finding of a testicular mass on scrotal ultrasonography during evaluation of hydroceles or varicoceles or during diagnostic workup for infertility. Leydig cell tumors have been primarily managed with radical inguinal orchiectomy. However, conservative management with testis-sparing surgery in younger adults and children were reported in the literature. Here we report a case of bilateral Leydig cell tumor of the testis treated with radical orchiectomy who presented with the complaint of infertilityand no disease recurrence in followup for 9 months. The patient is currently disease-free and under androgen supplemantation for androgen insufficiency. We recommend complete exam and diagnostic workup in patients with infertility and azoospermia. Termedia Publishing House 2012-09-29 2012 /pmc/articles/PMC3687425/ /pubmed/23788910 http://dx.doi.org/10.5114/wo.2012.30069 Text en Copyright © 2012 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sönmez, Nurettin
Ton, Özlem
Arısan, Serdar
Kılınç, Fatih
Eken, Kamile
Güney, Soner
Bilateral Leydig cell tumor of the testis: a case report
title Bilateral Leydig cell tumor of the testis: a case report
title_full Bilateral Leydig cell tumor of the testis: a case report
title_fullStr Bilateral Leydig cell tumor of the testis: a case report
title_full_unstemmed Bilateral Leydig cell tumor of the testis: a case report
title_short Bilateral Leydig cell tumor of the testis: a case report
title_sort bilateral leydig cell tumor of the testis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687425/
https://www.ncbi.nlm.nih.gov/pubmed/23788910
http://dx.doi.org/10.5114/wo.2012.30069
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