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Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence
The purpose of this paper is to systematically review the experimental and human studies on obesogenic chemicals and their mechanisms of action to provide a comprehensive view on the multifactorial aspects of obesity. The literatures were searched in available databases. The relevant papers were sel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687513/ https://www.ncbi.nlm.nih.gov/pubmed/23840234 http://dx.doi.org/10.1155/2013/896789 |
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author | Kelishadi, Roya Poursafa, Parinaz Jamshidi, Fahimeh |
author_facet | Kelishadi, Roya Poursafa, Parinaz Jamshidi, Fahimeh |
author_sort | Kelishadi, Roya |
collection | PubMed |
description | The purpose of this paper is to systematically review the experimental and human studies on obesogenic chemicals and their mechanisms of action to provide a comprehensive view on the multifactorial aspects of obesity. The literatures were searched in available databases. The relevant papers were selected in three phases. After quality assessment, two reviewers extracted the data while another checked their extracted data. In this review, we summarized information regarding environmental chemicals that can be associated with obesity. Most evidence comes from experimental and laboratory studies; however a growing number of human studies also support the role of obesogenic chemicals. The current evidence proposes that the systemic responses to exposure to environmental factors could potentially increase the risk of excess weight. The effects of exposure to these chemicals are of crucial importance during developmental phases of life, when preprogramming for an adipogenic outcome may occur. By considering the adverse transgenerational effects of obesogen chemicals on human health, the global obesity epidemic should be considered as a multifactorial complex disorder necessitating the emphasis of public health interventions for environmental protection. |
format | Online Article Text |
id | pubmed-3687513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36875132013-07-09 Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence Kelishadi, Roya Poursafa, Parinaz Jamshidi, Fahimeh J Environ Public Health Review Article The purpose of this paper is to systematically review the experimental and human studies on obesogenic chemicals and their mechanisms of action to provide a comprehensive view on the multifactorial aspects of obesity. The literatures were searched in available databases. The relevant papers were selected in three phases. After quality assessment, two reviewers extracted the data while another checked their extracted data. In this review, we summarized information regarding environmental chemicals that can be associated with obesity. Most evidence comes from experimental and laboratory studies; however a growing number of human studies also support the role of obesogenic chemicals. The current evidence proposes that the systemic responses to exposure to environmental factors could potentially increase the risk of excess weight. The effects of exposure to these chemicals are of crucial importance during developmental phases of life, when preprogramming for an adipogenic outcome may occur. By considering the adverse transgenerational effects of obesogen chemicals on human health, the global obesity epidemic should be considered as a multifactorial complex disorder necessitating the emphasis of public health interventions for environmental protection. Hindawi Publishing Corporation 2013 2013-06-05 /pmc/articles/PMC3687513/ /pubmed/23840234 http://dx.doi.org/10.1155/2013/896789 Text en Copyright © 2013 Roya Kelishadi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kelishadi, Roya Poursafa, Parinaz Jamshidi, Fahimeh Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence |
title | Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence |
title_full | Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence |
title_fullStr | Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence |
title_full_unstemmed | Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence |
title_short | Role of Environmental Chemicals in Obesity: A Systematic Review on the Current Evidence |
title_sort | role of environmental chemicals in obesity: a systematic review on the current evidence |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687513/ https://www.ncbi.nlm.nih.gov/pubmed/23840234 http://dx.doi.org/10.1155/2013/896789 |
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