Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite

CD8 T cells protect the host from disease caused by intracellular pathogens, such as the Toxoplasma gondii (T. gondii) protozoan parasite. Despite the complexity of the T. gondii proteome, CD8 T cell responses are restricted to only a small number of peptide epitopes derived from a limited set of an...

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Detalles Bibliográficos
Autores principales: Feliu, Virginie, Vasseur, Virginie, Grover, Harshita S., Chu, H. Hamlet, Brown, Mark J., Wang, Jeremy, Boyle, Jon P., Robey, Ellen A., Shastri, Nilabh, Blanchard, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688528/
https://www.ncbi.nlm.nih.gov/pubmed/23818852
http://dx.doi.org/10.1371/journal.ppat.1003449

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