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The Th17/Treg Ratio, IL-1RA and sCD14 Levels in Primary HIV Infection Predict the T-cell Activation Set Point in the Absence of Systemic Microbial Translocation
Impairment of the intestinal barrier and subsequent microbial translocation (MT) may be involved in chronic immune activation, which plays a central role in HIV pathogenesis. Th17 cells are critical to prevent MT. The aim of the study was to investigate, in patients with primary HIV infection (PHI),...
Autores principales: | Chevalier, Mathieu F., Petitjean, Gaël, Dunyach-Rémy, Catherine, Didier, Céline, Girard, Pierre-Marie, Manea, Maria Elena, Campa, Pauline, Meyer, Laurence, Rouzioux, Christine, Lavigne, Jean-Philippe, Barré-Sinoussi, Françoise, Scott-Algara, Daniel, Weiss, Laurence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688532/ https://www.ncbi.nlm.nih.gov/pubmed/23818854 http://dx.doi.org/10.1371/journal.ppat.1003453 |
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