Extreme Genetic Fragility of the HIV-1 Capsid

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Genetic robustness, or fragility, is defined as the ability, or lack thereof, of a biological entity to maintain function in the face of mutations. Viruses that replicate via RNA intermediates exhibit high mutation rates, and robustness should be particularly advantageous to them. The capsid (CA) do...

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Detalles Bibliográficos
Autores principales: Rihn, Suzannah J., Wilson, Sam J., Loman, Nick J., Alim, Mudathir, Bakker, Saskia E., Bhella, David, Gifford, Robert J., Rixon, Frazer J., Bieniasz, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688543/
https://www.ncbi.nlm.nih.gov/pubmed/23818857
http://dx.doi.org/10.1371/journal.ppat.1003461
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