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Nitric Oxide Synthase Dysfunction Contributes to Impaired Cerebroarteriolar Reactivity in Experimental Cerebral Malaria
Cerebrovascular dysfunction plays a key role in the pathogenesis of cerebral malaria. In experimental cerebral malaria (ECM) induced by Plasmodium berghei ANKA, cerebrovascular dysfunction characterized by vascular constriction, occlusion and damage results in impaired perfusion and reduced cerebral...
Autores principales: | Ong, Peng Kai, Melchior, Benoît, Martins, Yuri C., Hofer, Anthony, Orjuela-Sánchez, Pamela, Cabrales, Pedro, Zanini, Graziela M., Frangos, John A., Carvalho, Leonardo J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688552/ https://www.ncbi.nlm.nih.gov/pubmed/23818850 http://dx.doi.org/10.1371/journal.ppat.1003444 |
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