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Homocysteine Restricts Copper Availability Leading to Suppression of Cytochrome C Oxidase Activity in Phenylephrine-Treated Cardiomyocytes

Cardiomyocyte hypertrophy induced by phenylephrine (PE) is accompanied by suppression of cytochrome c oxidase (CCO) activity, and copper (Cu) supplementation restores CCO activity and reverses the hypertrophy. The present study was aimed to understand the mechanism of PE-induced decrease in CCO acti...

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Detalles Bibliográficos
Autores principales:	Zuo, Xiao, Dong, Daoyin, Sun, Miao, Xie, Huiqi, Kang, Y. James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688604/ https://www.ncbi.nlm.nih.gov/pubmed/23818984 http://dx.doi.org/10.1371/journal.pone.0067549

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