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p53 Selectively Regulates Developmental Apoptosis of Rod Photoreceptors

Retinal cells become post-mitotic early during post-natal development. It is likely that p53, a well-known cell cycle regulator, is involved in regulating the genesis, differentiation and death of retinal cells. Furthermore, retinal cells are under constant oxidative stress that can result in DNA da...

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Detalles Bibliográficos
Autores principales: Vuong, Linda, Brobst, Daniel E., Ivanovic, Ivana, Sherry, David M., Al-Ubaidi, Muayyad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688626/
https://www.ncbi.nlm.nih.gov/pubmed/23840687
http://dx.doi.org/10.1371/journal.pone.0067381