Lin28 Mediates Radiation Resistance of Breast Cancer Cells via Regulation of Caspase, H2A.X and Let-7 Signaling

Resistance to radiation therapy is a major obstacle for the effective treatment of cancers. Lin28 has been shown to contribute to breast tumorigenesis; however, the relationship between Lin28 and radioresistance remains unknown. In this study, we investigated the association of Lin28 with radiation...

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Detalles Bibliográficos
Autores principales: Wang, Linbo, Yuan, Chao, Lv, Kezhen, Xie, Shuduo, Fu, Peifen, Liu, Xiaojiao, Chen, Yongxia, Qin, Chuan, Deng, Wuguo, Hu, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688678/
https://www.ncbi.nlm.nih.gov/pubmed/23840685
http://dx.doi.org/10.1371/journal.pone.0067373

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