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Celiac Disease–Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics
A characteristic feature of celiac disease is the presence of circulating autoantibodies targeted against transglutaminase 2 (TG2), reputed to have a function in angiogenesis. In this study we investigated whether TG2-specific autoantibodies derived from celiac patients inhibit angiogenesis in both...
Autores principales: | Kalliokoski, Suvi, Sulic, Ana-Marija, Korponay-Szabó, Ilma R., Szondy, Zsuzsa, Frias, Rafael, Perez, Mileidys Alea, Martucciello, Stefania, Roivainen, Anne, Pelliniemi, Lauri J., Esposito, Carla, Griffin, Martin, Sblattero, Daniele, Mäki, Markku, Kaukinen, Katri, Lindfors, Katri, Caja, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688809/ https://www.ncbi.nlm.nih.gov/pubmed/23824706 http://dx.doi.org/10.1371/journal.pone.0065887 |
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