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TLR3, TLR4 and TLRs7–9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma
Defective Rhinovirus induced interferon-β and interferon-λ production has been reported in bronchial epithelial cells from asthmatics but the mechanisms of defective interferon induction in asthma are unknown. Virus infection can induce interferon through Toll like Receptors (TLR)3, TLR7 and TLR8. T...
Autores principales: | Sykes, Annemarie, Edwards, Michael R., Macintyre, Jonathan, del Rosario, Ajerico, Gielen, Vera, Haas, Jennifer, Kon, Onn Min, McHale, Mark, Johnston, Sebastian L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688823/ https://www.ncbi.nlm.nih.gov/pubmed/23824215 http://dx.doi.org/10.1371/journal.pone.0065921 |
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