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Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study

BACKGROUND: HIV-2 is endemic in West Africa. There is a lack of evidence-based guidelines on the diagnosis, management and antiretroviral therapy (ART) for HIV-2 or HIV-1/HIV-2 dual infections. Because of these issues, we designed a West African collaborative cohort for HIV-2 infection within the fr...

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Autores principales: Ekouevi, Didier K., Balestre, Eric, Coffie, Patrick A., Minta, Daouda, Messou, Eugene, Sawadogo, Adrien, Minga, Albert, Sow, Papa Salif, Bissagnene, Emmanuel, Eholie, Serge P., Gottlieb, Geoffrey S., Dabis, François, Zannou, Djimon Marcel, Ahouada, Carin, Akakpo, Jocelyn, Ahomadegbé, Christelle, Bashi, Jules, Gougounon-Houéto, Alice, Azon-Kouanou, Angèle, Houngbé, Fabien, Koumakpaï, Sikiratou, Alihonou, Florence, d’Almeida, Marcelline, Hodonou, Irvine, Hounhoui, Ghislaine, Sagbo, Gracien, Tossa-Bagnan, Leïla, Adjide, Herman, Drabo, Joseph, Bognounou, René, Dienderé, Arnaud, Traore, Eliezer, Zoungrana, Lassane, Zerbo, Béatrice, Sawadogo, Adrien Bruno, Zoungrana, Jacques, Héma, Arsène, Soré, Ibrahim, Bado, Guillaume, Tapsoba, Achille, Yé, Diarra, Kouéta, Fla, Ouedraogo, Sylvie, Ouédraogo, Rasmata, Hiembo, William, Gansonré, Mady, Messou, Eugène, Gnokoro, Joachim Charles, Koné, Mamadou, Kouakou, Guillaume Martial, Bosse, Clarisse Amani, Brou, Kouakou, Assi, Achi Isidore, Chenal, Henri, Hawerlander, Denise, Soppi, Franck, Abo, Yao, Bomisso, Germain, Eholié, Serge Paul, Amego, Mensah Deborah Noelly, Andavi, Viviane, Diallo, Zelica, Ello, Frédéric, Tanon, Aristophane Koffi, Koule, Serge Olivier, Anzan, Koffi Charles, Guehi, Calixte, Aka, Edmond Addi, Issouf, Koffi Ladji, Kouakou, Jean-Claude, N’Gbeche, Marie-Sylvie, Touré, Pety, Avit-Edi, Divine, Kouakou, Kouadio, Moh, Magloire, Yao, Valérie Andoblé, Folquet, Madeleine Amorissani, Dainguy, Marie-Evelyne, Kouakou, Cyrille, Méa-Assande, Véronique Tanoh, Oka-Berete, Gladys, Zobo, Nathalie, Acquah, Patrick, Kokora, Marie-Berthe, Eboua, Tanoh François, Timité-Konan, Marguerite, Ahoussou, Lucrèce Diecket, Assouan, Julie Kebé, Sami, Mabéa Flora, Kouadio, Clémence, Renner, Lorna, Goka, Bamenla, Welbeck, Jennifer, Sackey, Adziri, Owiafe, Seth Ntiri, Wejse, Christian, Silva, Zacarias José Da, Paulo, Joao, Rodrigues, Amabelia, da Silva, David, Medina, Candida, Oliviera-Souto, Ines, Østergaard, Lars, Laursen, Alex, Sodemann, Morten, Aaby, Peter, Fomsgaard, Anders, Erikstrup, Christian, Eugen-Olsen, Jesper, Maïga, Moussa Y, Diakité, Fatoumata Fofana, Kalle, Abdoulaye, Katile, Drissa, Traore, Hamar Alassane, Cissé, Tidiani, Dembelé, Mamadou, Doumbia, Mohammed, Fomba, Mahamadou, Kaya, Assétou Soukho, Traoré, Abdoulaye M, Traoré, Hamady, Toure, Amadou Abathina, Dicko, Fatoumata, Sylla, Mariam, Berthé, Alima, Traoré, Hadizatou Coulibaly, Koïta, Anta, Koné, Niaboula, N'Diaye, Clémentine, Coulibaly, Safiatou Touré, Traoré, Mamadou, Traoré, Naïchata, Charurat, Man, Ajayi, Samuel, Dapiap, Stephen, Otu, Igbinoba, Festus, Benson, Okwara, Adebamowo, Clément, James, Jesse, Obaseki, Osakede, Philip, Olasode, John, Diop, Bernard, Manga, Noël Magloire, Tine, Judicael Malick, Signate Sy, Haby, Ba, Abou, Diagne, Aida, Dior, Hélène, Faye, Malick, Gueye, Ramatoulaye Diagne, Mbaye, Aminata Diack, Patassi, Akessiwe, Kotosso, Awèrou, Kariyare, Benjamin Goilibe, Gbadamassi, Gafarou, Komi, Agbo, Mensah-Zukong, Kankoé Edem, Pakpame, Pinuwe, Lawson-Evi, Annette Koko, Atakouma, Yawo, Takassi, Elom, Djeha, Améyo, Ephoévi-gah, Ayoko, Djibril, Sherifa El-Hadj, Arrivé, Elise, Coffie, Patrick, Ekouevi, Didier, Jaquet, Antoine, Leroy, Valériane, Lewden, Charlotte, Sasco, Annie, Azani, Jean-Claude, Allou, Gérard, Bohossou, Franck, Karcher, Sophie, Gonsan, Jules Mahan, Carrou, Jérôme Le, Lenaud, Séverin, Nchot, Célestin, Malateste, Karen, Yao, Amon Roseamonde, Siloué, Bertine, Clouet, Gwenaelle, Djetouan, Hugues, Doring, Alexandra, Kouakou, Adrienne, Rabourdin, Elodie, Rivenc, Jean, Anglaret, Xavier, Ba, Boubacar, Essanin, Jean Bosco, Ciaranello, Andrea, Datté, Sébastien, Desmonde, Sophie, Diby, Jean-Serge Elvis, Horo, Apollinaire Gninlgninrin, Kangah, Serge N'zoré, Malvy, Denis, Meless, David, Mounkaila-Harouna, Aida, Ndondoki, Camille, Shiboski, Caroline, Thiébaut, Rodolphe, PAC-CI, Abidjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688850/
https://www.ncbi.nlm.nih.gov/pubmed/23824279
http://dx.doi.org/10.1371/journal.pone.0066135
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author Ekouevi, Didier K.
Balestre, Eric
Coffie, Patrick A.
Minta, Daouda
Messou, Eugene
Sawadogo, Adrien
Minga, Albert
Sow, Papa Salif
Bissagnene, Emmanuel
Eholie, Serge P.
Gottlieb, Geoffrey S.
Dabis, François
Zannou, Djimon Marcel
Ahouada, Carin
Akakpo, Jocelyn
Ahomadegbé, Christelle
Bashi, Jules
Gougounon-Houéto, Alice
Azon-Kouanou, Angèle
Houngbé, Fabien
Koumakpaï, Sikiratou
Alihonou, Florence
d’Almeida, Marcelline
Hodonou, Irvine
Hounhoui, Ghislaine
Sagbo, Gracien
Tossa-Bagnan, Leïla
Adjide, Herman
Drabo, Joseph
Bognounou, René
Dienderé, Arnaud
Traore, Eliezer
Zoungrana, Lassane
Zerbo, Béatrice
Sawadogo, Adrien Bruno
Zoungrana, Jacques
Héma, Arsène
Soré, Ibrahim
Bado, Guillaume
Tapsoba, Achille
Yé, Diarra
Kouéta, Fla
Ouedraogo, Sylvie
Ouédraogo, Rasmata
Hiembo, William
Gansonré, Mady
Messou, Eugène
Gnokoro, Joachim Charles
Koné, Mamadou
Kouakou, Guillaume Martial
Bosse, Clarisse Amani
Brou, Kouakou
Assi, Achi Isidore
Chenal, Henri
Hawerlander, Denise
Soppi, Franck
Minga, Albert
Abo, Yao
Bomisso, Germain
Eholié, Serge Paul
Amego, Mensah Deborah Noelly
Andavi, Viviane
Diallo, Zelica
Ello, Frédéric
Tanon, Aristophane Koffi
Koule, Serge Olivier
Anzan, Koffi Charles
Guehi, Calixte
Aka, Edmond Addi
Issouf, Koffi Ladji
Kouakou, Jean-Claude
N’Gbeche, Marie-Sylvie
Touré, Pety
Avit-Edi, Divine
Kouakou, Kouadio
Moh, Magloire
Yao, Valérie Andoblé
Folquet, Madeleine Amorissani
Dainguy, Marie-Evelyne
Kouakou, Cyrille
Méa-Assande, Véronique Tanoh
Oka-Berete, Gladys
Zobo, Nathalie
Acquah, Patrick
Kokora, Marie-Berthe
Eboua, Tanoh François
Timité-Konan, Marguerite
Ahoussou, Lucrèce Diecket
Assouan, Julie Kebé
Sami, Mabéa Flora
Kouadio, Clémence
Renner, Lorna
Goka, Bamenla
Welbeck, Jennifer
Sackey, Adziri
Owiafe, Seth Ntiri
Wejse, Christian
Silva, Zacarias José Da
Paulo, Joao
Rodrigues, Amabelia
da Silva, David
Medina, Candida
Oliviera-Souto, Ines
Østergaard, Lars
Laursen, Alex
Sodemann, Morten
Aaby, Peter
Fomsgaard, Anders
Erikstrup, Christian
Eugen-Olsen, Jesper
Maïga, Moussa Y
Diakité, Fatoumata Fofana
Kalle, Abdoulaye
Katile, Drissa
Traore, Hamar Alassane
Minta, Daouda
Cissé, Tidiani
Dembelé, Mamadou
Doumbia, Mohammed
Fomba, Mahamadou
Kaya, Assétou Soukho
Traoré, Abdoulaye M
Traoré, Hamady
Toure, Amadou Abathina
Dicko, Fatoumata
Sylla, Mariam
Berthé, Alima
Traoré, Hadizatou Coulibaly
Koïta, Anta
Koné, Niaboula
N'Diaye, Clémentine
Coulibaly, Safiatou Touré
Traoré, Mamadou
Traoré, Naïchata
Charurat, Man
Ajayi, Samuel
Dapiap, Stephen
Otu,
Igbinoba, Festus
Benson, Okwara
Adebamowo, Clément
James, Jesse
Obaseki,
Osakede, Philip
Olasode, John
Sow, Papa Salif
Diop, Bernard
Manga, Noël Magloire
Tine, Judicael Malick
Signate Sy, Haby
Ba, Abou
Diagne, Aida
Dior, Hélène
Faye, Malick
Gueye, Ramatoulaye Diagne
Mbaye, Aminata Diack
Patassi, Akessiwe
Kotosso, Awèrou
Kariyare, Benjamin Goilibe
Gbadamassi, Gafarou
Komi, Agbo
Mensah-Zukong, Kankoé Edem
Pakpame, Pinuwe
Lawson-Evi, Annette Koko
Atakouma, Yawo
Takassi, Elom
Djeha, Améyo
Ephoévi-gah, Ayoko
Djibril, Sherifa El-Hadj
Dabis, François
Bissagnene, Emmanuel
Arrivé, Elise
Coffie, Patrick
Ekouevi, Didier
Jaquet, Antoine
Leroy, Valériane
Lewden, Charlotte
Sasco, Annie
Azani, Jean-Claude
Allou, Gérard
Balestre, Eric
Bohossou, Franck
Karcher, Sophie
Gonsan, Jules Mahan
Carrou, Jérôme Le
Lenaud, Séverin
Nchot, Célestin
Malateste, Karen
Yao, Amon Roseamonde
Siloué, Bertine
Clouet, Gwenaelle
Djetouan, Hugues
Doring, Alexandra
Kouakou, Adrienne
Rabourdin, Elodie
Rivenc, Jean
Anglaret, Xavier
Ba, Boubacar
Essanin, Jean Bosco
Ciaranello, Andrea
Datté, Sébastien
Desmonde, Sophie
Diby, Jean-Serge Elvis
Gottlieb, Geoffrey S.
Horo, Apollinaire Gninlgninrin
Kangah, Serge N'zoré
Malvy, Denis
Meless, David
Mounkaila-Harouna, Aida
Ndondoki, Camille
Shiboski, Caroline
Thiébaut, Rodolphe
PAC-CI,
Abidjan,
author_facet Ekouevi, Didier K.
Balestre, Eric
Coffie, Patrick A.
Minta, Daouda
Messou, Eugene
Sawadogo, Adrien
Minga, Albert
Sow, Papa Salif
Bissagnene, Emmanuel
Eholie, Serge P.
Gottlieb, Geoffrey S.
Dabis, François
Zannou, Djimon Marcel
Ahouada, Carin
Akakpo, Jocelyn
Ahomadegbé, Christelle
Bashi, Jules
Gougounon-Houéto, Alice
Azon-Kouanou, Angèle
Houngbé, Fabien
Koumakpaï, Sikiratou
Alihonou, Florence
d’Almeida, Marcelline
Hodonou, Irvine
Hounhoui, Ghislaine
Sagbo, Gracien
Tossa-Bagnan, Leïla
Adjide, Herman
Drabo, Joseph
Bognounou, René
Dienderé, Arnaud
Traore, Eliezer
Zoungrana, Lassane
Zerbo, Béatrice
Sawadogo, Adrien Bruno
Zoungrana, Jacques
Héma, Arsène
Soré, Ibrahim
Bado, Guillaume
Tapsoba, Achille
Yé, Diarra
Kouéta, Fla
Ouedraogo, Sylvie
Ouédraogo, Rasmata
Hiembo, William
Gansonré, Mady
Messou, Eugène
Gnokoro, Joachim Charles
Koné, Mamadou
Kouakou, Guillaume Martial
Bosse, Clarisse Amani
Brou, Kouakou
Assi, Achi Isidore
Chenal, Henri
Hawerlander, Denise
Soppi, Franck
Minga, Albert
Abo, Yao
Bomisso, Germain
Eholié, Serge Paul
Amego, Mensah Deborah Noelly
Andavi, Viviane
Diallo, Zelica
Ello, Frédéric
Tanon, Aristophane Koffi
Koule, Serge Olivier
Anzan, Koffi Charles
Guehi, Calixte
Aka, Edmond Addi
Issouf, Koffi Ladji
Kouakou, Jean-Claude
N’Gbeche, Marie-Sylvie
Touré, Pety
Avit-Edi, Divine
Kouakou, Kouadio
Moh, Magloire
Yao, Valérie Andoblé
Folquet, Madeleine Amorissani
Dainguy, Marie-Evelyne
Kouakou, Cyrille
Méa-Assande, Véronique Tanoh
Oka-Berete, Gladys
Zobo, Nathalie
Acquah, Patrick
Kokora, Marie-Berthe
Eboua, Tanoh François
Timité-Konan, Marguerite
Ahoussou, Lucrèce Diecket
Assouan, Julie Kebé
Sami, Mabéa Flora
Kouadio, Clémence
Renner, Lorna
Goka, Bamenla
Welbeck, Jennifer
Sackey, Adziri
Owiafe, Seth Ntiri
Wejse, Christian
Silva, Zacarias José Da
Paulo, Joao
Rodrigues, Amabelia
da Silva, David
Medina, Candida
Oliviera-Souto, Ines
Østergaard, Lars
Laursen, Alex
Sodemann, Morten
Aaby, Peter
Fomsgaard, Anders
Erikstrup, Christian
Eugen-Olsen, Jesper
Maïga, Moussa Y
Diakité, Fatoumata Fofana
Kalle, Abdoulaye
Katile, Drissa
Traore, Hamar Alassane
Minta, Daouda
Cissé, Tidiani
Dembelé, Mamadou
Doumbia, Mohammed
Fomba, Mahamadou
Kaya, Assétou Soukho
Traoré, Abdoulaye M
Traoré, Hamady
Toure, Amadou Abathina
Dicko, Fatoumata
Sylla, Mariam
Berthé, Alima
Traoré, Hadizatou Coulibaly
Koïta, Anta
Koné, Niaboula
N'Diaye, Clémentine
Coulibaly, Safiatou Touré
Traoré, Mamadou
Traoré, Naïchata
Charurat, Man
Ajayi, Samuel
Dapiap, Stephen
Otu,
Igbinoba, Festus
Benson, Okwara
Adebamowo, Clément
James, Jesse
Obaseki,
Osakede, Philip
Olasode, John
Sow, Papa Salif
Diop, Bernard
Manga, Noël Magloire
Tine, Judicael Malick
Signate Sy, Haby
Ba, Abou
Diagne, Aida
Dior, Hélène
Faye, Malick
Gueye, Ramatoulaye Diagne
Mbaye, Aminata Diack
Patassi, Akessiwe
Kotosso, Awèrou
Kariyare, Benjamin Goilibe
Gbadamassi, Gafarou
Komi, Agbo
Mensah-Zukong, Kankoé Edem
Pakpame, Pinuwe
Lawson-Evi, Annette Koko
Atakouma, Yawo
Takassi, Elom
Djeha, Améyo
Ephoévi-gah, Ayoko
Djibril, Sherifa El-Hadj
Dabis, François
Bissagnene, Emmanuel
Arrivé, Elise
Coffie, Patrick
Ekouevi, Didier
Jaquet, Antoine
Leroy, Valériane
Lewden, Charlotte
Sasco, Annie
Azani, Jean-Claude
Allou, Gérard
Balestre, Eric
Bohossou, Franck
Karcher, Sophie
Gonsan, Jules Mahan
Carrou, Jérôme Le
Lenaud, Séverin
Nchot, Célestin
Malateste, Karen
Yao, Amon Roseamonde
Siloué, Bertine
Clouet, Gwenaelle
Djetouan, Hugues
Doring, Alexandra
Kouakou, Adrienne
Rabourdin, Elodie
Rivenc, Jean
Anglaret, Xavier
Ba, Boubacar
Essanin, Jean Bosco
Ciaranello, Andrea
Datté, Sébastien
Desmonde, Sophie
Diby, Jean-Serge Elvis
Gottlieb, Geoffrey S.
Horo, Apollinaire Gninlgninrin
Kangah, Serge N'zoré
Malvy, Denis
Meless, David
Mounkaila-Harouna, Aida
Ndondoki, Camille
Shiboski, Caroline
Thiébaut, Rodolphe
PAC-CI,
Abidjan,
author_sort Ekouevi, Didier K.
collection PubMed
description BACKGROUND: HIV-2 is endemic in West Africa. There is a lack of evidence-based guidelines on the diagnosis, management and antiretroviral therapy (ART) for HIV-2 or HIV-1/HIV-2 dual infections. Because of these issues, we designed a West African collaborative cohort for HIV-2 infection within the framework of the International epidemiological Databases to Evaluate AIDS (IeDEA). METHODS: We collected data on all HIV-2 and HIV-1/HIV-2 dually seropositive patients (both ARV-naive and starting ART) and followed-up in clinical centres in the IeDEA-WA network including a total of 13 clinics in five countries: Benin, Burkina-Faso Côte d’Ivoire, Mali, and Senegal, in the West Africa region. RESULTS: Data was merged for 1,754 patients (56% female), including 1,021 HIV-2 infected patients (551 on ART) and 733 dually seropositive for both HIV-1 and HIV 2 (463 on ART). At ART initiation, the median age of HIV-2 patients was 45.3 years, IQR: (38.3–51.7) and 42.4 years, IQR (37.0–47.3) for dually seropositive patients (p = 0.048). Overall, 16.7% of HIV-2 patients on ART had an advanced clinical stage (WHO IV or CDC-C). The median CD4 count at the ART initiation is 166 cells/mm(3), IQR (83–247) among HIV-2 infected patients and 146 cells/mm(3), IQR (55–249) among dually seropositive patients. Overall, in ART-treated patients, the CD4 count increased 126 cells/mm(3) after 24 months on ART for HIV-2 patients and 169 cells/mm(3) for dually seropositive patients. Of 551 HIV-2 patients on ART, 5.8% died and 10.2% were lost to follow-up during the median time on ART of 2.4 years, IQR (0.7–4.3). CONCLUSIONS: This large multi-country study of HIV-2 and HIV-1/HIV-2 dual infection in West Africa suggests that routine clinical care is less than optimal and that management and treatment of HIV-2 could be further informed by ongoing studies and randomized clinical trials in this population.
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spelling pubmed-36888502013-07-02 Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study Ekouevi, Didier K. Balestre, Eric Coffie, Patrick A. Minta, Daouda Messou, Eugene Sawadogo, Adrien Minga, Albert Sow, Papa Salif Bissagnene, Emmanuel Eholie, Serge P. Gottlieb, Geoffrey S. Dabis, François Zannou, Djimon Marcel Ahouada, Carin Akakpo, Jocelyn Ahomadegbé, Christelle Bashi, Jules Gougounon-Houéto, Alice Azon-Kouanou, Angèle Houngbé, Fabien Koumakpaï, Sikiratou Alihonou, Florence d’Almeida, Marcelline Hodonou, Irvine Hounhoui, Ghislaine Sagbo, Gracien Tossa-Bagnan, Leïla Adjide, Herman Drabo, Joseph Bognounou, René Dienderé, Arnaud Traore, Eliezer Zoungrana, Lassane Zerbo, Béatrice Sawadogo, Adrien Bruno Zoungrana, Jacques Héma, Arsène Soré, Ibrahim Bado, Guillaume Tapsoba, Achille Yé, Diarra Kouéta, Fla Ouedraogo, Sylvie Ouédraogo, Rasmata Hiembo, William Gansonré, Mady Messou, Eugène Gnokoro, Joachim Charles Koné, Mamadou Kouakou, Guillaume Martial Bosse, Clarisse Amani Brou, Kouakou Assi, Achi Isidore Chenal, Henri Hawerlander, Denise Soppi, Franck Minga, Albert Abo, Yao Bomisso, Germain Eholié, Serge Paul Amego, Mensah Deborah Noelly Andavi, Viviane Diallo, Zelica Ello, Frédéric Tanon, Aristophane Koffi Koule, Serge Olivier Anzan, Koffi Charles Guehi, Calixte Aka, Edmond Addi Issouf, Koffi Ladji Kouakou, Jean-Claude N’Gbeche, Marie-Sylvie Touré, Pety Avit-Edi, Divine Kouakou, Kouadio Moh, Magloire Yao, Valérie Andoblé Folquet, Madeleine Amorissani Dainguy, Marie-Evelyne Kouakou, Cyrille Méa-Assande, Véronique Tanoh Oka-Berete, Gladys Zobo, Nathalie Acquah, Patrick Kokora, Marie-Berthe Eboua, Tanoh François Timité-Konan, Marguerite Ahoussou, Lucrèce Diecket Assouan, Julie Kebé Sami, Mabéa Flora Kouadio, Clémence Renner, Lorna Goka, Bamenla Welbeck, Jennifer Sackey, Adziri Owiafe, Seth Ntiri Wejse, Christian Silva, Zacarias José Da Paulo, Joao Rodrigues, Amabelia da Silva, David Medina, Candida Oliviera-Souto, Ines Østergaard, Lars Laursen, Alex Sodemann, Morten Aaby, Peter Fomsgaard, Anders Erikstrup, Christian Eugen-Olsen, Jesper Maïga, Moussa Y Diakité, Fatoumata Fofana Kalle, Abdoulaye Katile, Drissa Traore, Hamar Alassane Minta, Daouda Cissé, Tidiani Dembelé, Mamadou Doumbia, Mohammed Fomba, Mahamadou Kaya, Assétou Soukho Traoré, Abdoulaye M Traoré, Hamady Toure, Amadou Abathina Dicko, Fatoumata Sylla, Mariam Berthé, Alima Traoré, Hadizatou Coulibaly Koïta, Anta Koné, Niaboula N'Diaye, Clémentine Coulibaly, Safiatou Touré Traoré, Mamadou Traoré, Naïchata Charurat, Man Ajayi, Samuel Dapiap, Stephen Otu, Igbinoba, Festus Benson, Okwara Adebamowo, Clément James, Jesse Obaseki, Osakede, Philip Olasode, John Sow, Papa Salif Diop, Bernard Manga, Noël Magloire Tine, Judicael Malick Signate Sy, Haby Ba, Abou Diagne, Aida Dior, Hélène Faye, Malick Gueye, Ramatoulaye Diagne Mbaye, Aminata Diack Patassi, Akessiwe Kotosso, Awèrou Kariyare, Benjamin Goilibe Gbadamassi, Gafarou Komi, Agbo Mensah-Zukong, Kankoé Edem Pakpame, Pinuwe Lawson-Evi, Annette Koko Atakouma, Yawo Takassi, Elom Djeha, Améyo Ephoévi-gah, Ayoko Djibril, Sherifa El-Hadj Dabis, François Bissagnene, Emmanuel Arrivé, Elise Coffie, Patrick Ekouevi, Didier Jaquet, Antoine Leroy, Valériane Lewden, Charlotte Sasco, Annie Azani, Jean-Claude Allou, Gérard Balestre, Eric Bohossou, Franck Karcher, Sophie Gonsan, Jules Mahan Carrou, Jérôme Le Lenaud, Séverin Nchot, Célestin Malateste, Karen Yao, Amon Roseamonde Siloué, Bertine Clouet, Gwenaelle Djetouan, Hugues Doring, Alexandra Kouakou, Adrienne Rabourdin, Elodie Rivenc, Jean Anglaret, Xavier Ba, Boubacar Essanin, Jean Bosco Ciaranello, Andrea Datté, Sébastien Desmonde, Sophie Diby, Jean-Serge Elvis Gottlieb, Geoffrey S. Horo, Apollinaire Gninlgninrin Kangah, Serge N'zoré Malvy, Denis Meless, David Mounkaila-Harouna, Aida Ndondoki, Camille Shiboski, Caroline Thiébaut, Rodolphe PAC-CI, Abidjan, PLoS One Research Article BACKGROUND: HIV-2 is endemic in West Africa. There is a lack of evidence-based guidelines on the diagnosis, management and antiretroviral therapy (ART) for HIV-2 or HIV-1/HIV-2 dual infections. Because of these issues, we designed a West African collaborative cohort for HIV-2 infection within the framework of the International epidemiological Databases to Evaluate AIDS (IeDEA). METHODS: We collected data on all HIV-2 and HIV-1/HIV-2 dually seropositive patients (both ARV-naive and starting ART) and followed-up in clinical centres in the IeDEA-WA network including a total of 13 clinics in five countries: Benin, Burkina-Faso Côte d’Ivoire, Mali, and Senegal, in the West Africa region. RESULTS: Data was merged for 1,754 patients (56% female), including 1,021 HIV-2 infected patients (551 on ART) and 733 dually seropositive for both HIV-1 and HIV 2 (463 on ART). At ART initiation, the median age of HIV-2 patients was 45.3 years, IQR: (38.3–51.7) and 42.4 years, IQR (37.0–47.3) for dually seropositive patients (p = 0.048). Overall, 16.7% of HIV-2 patients on ART had an advanced clinical stage (WHO IV or CDC-C). The median CD4 count at the ART initiation is 166 cells/mm(3), IQR (83–247) among HIV-2 infected patients and 146 cells/mm(3), IQR (55–249) among dually seropositive patients. Overall, in ART-treated patients, the CD4 count increased 126 cells/mm(3) after 24 months on ART for HIV-2 patients and 169 cells/mm(3) for dually seropositive patients. Of 551 HIV-2 patients on ART, 5.8% died and 10.2% were lost to follow-up during the median time on ART of 2.4 years, IQR (0.7–4.3). CONCLUSIONS: This large multi-country study of HIV-2 and HIV-1/HIV-2 dual infection in West Africa suggests that routine clinical care is less than optimal and that management and treatment of HIV-2 could be further informed by ongoing studies and randomized clinical trials in this population. Public Library of Science 2013-06-18 /pmc/articles/PMC3688850/ /pubmed/23824279 http://dx.doi.org/10.1371/journal.pone.0066135 Text en © 2013 Ekouevi et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Ekouevi, Didier K.
Balestre, Eric
Coffie, Patrick A.
Minta, Daouda
Messou, Eugene
Sawadogo, Adrien
Minga, Albert
Sow, Papa Salif
Bissagnene, Emmanuel
Eholie, Serge P.
Gottlieb, Geoffrey S.
Dabis, François
Zannou, Djimon Marcel
Ahouada, Carin
Akakpo, Jocelyn
Ahomadegbé, Christelle
Bashi, Jules
Gougounon-Houéto, Alice
Azon-Kouanou, Angèle
Houngbé, Fabien
Koumakpaï, Sikiratou
Alihonou, Florence
d’Almeida, Marcelline
Hodonou, Irvine
Hounhoui, Ghislaine
Sagbo, Gracien
Tossa-Bagnan, Leïla
Adjide, Herman
Drabo, Joseph
Bognounou, René
Dienderé, Arnaud
Traore, Eliezer
Zoungrana, Lassane
Zerbo, Béatrice
Sawadogo, Adrien Bruno
Zoungrana, Jacques
Héma, Arsène
Soré, Ibrahim
Bado, Guillaume
Tapsoba, Achille
Yé, Diarra
Kouéta, Fla
Ouedraogo, Sylvie
Ouédraogo, Rasmata
Hiembo, William
Gansonré, Mady
Messou, Eugène
Gnokoro, Joachim Charles
Koné, Mamadou
Kouakou, Guillaume Martial
Bosse, Clarisse Amani
Brou, Kouakou
Assi, Achi Isidore
Chenal, Henri
Hawerlander, Denise
Soppi, Franck
Minga, Albert
Abo, Yao
Bomisso, Germain
Eholié, Serge Paul
Amego, Mensah Deborah Noelly
Andavi, Viviane
Diallo, Zelica
Ello, Frédéric
Tanon, Aristophane Koffi
Koule, Serge Olivier
Anzan, Koffi Charles
Guehi, Calixte
Aka, Edmond Addi
Issouf, Koffi Ladji
Kouakou, Jean-Claude
N’Gbeche, Marie-Sylvie
Touré, Pety
Avit-Edi, Divine
Kouakou, Kouadio
Moh, Magloire
Yao, Valérie Andoblé
Folquet, Madeleine Amorissani
Dainguy, Marie-Evelyne
Kouakou, Cyrille
Méa-Assande, Véronique Tanoh
Oka-Berete, Gladys
Zobo, Nathalie
Acquah, Patrick
Kokora, Marie-Berthe
Eboua, Tanoh François
Timité-Konan, Marguerite
Ahoussou, Lucrèce Diecket
Assouan, Julie Kebé
Sami, Mabéa Flora
Kouadio, Clémence
Renner, Lorna
Goka, Bamenla
Welbeck, Jennifer
Sackey, Adziri
Owiafe, Seth Ntiri
Wejse, Christian
Silva, Zacarias José Da
Paulo, Joao
Rodrigues, Amabelia
da Silva, David
Medina, Candida
Oliviera-Souto, Ines
Østergaard, Lars
Laursen, Alex
Sodemann, Morten
Aaby, Peter
Fomsgaard, Anders
Erikstrup, Christian
Eugen-Olsen, Jesper
Maïga, Moussa Y
Diakité, Fatoumata Fofana
Kalle, Abdoulaye
Katile, Drissa
Traore, Hamar Alassane
Minta, Daouda
Cissé, Tidiani
Dembelé, Mamadou
Doumbia, Mohammed
Fomba, Mahamadou
Kaya, Assétou Soukho
Traoré, Abdoulaye M
Traoré, Hamady
Toure, Amadou Abathina
Dicko, Fatoumata
Sylla, Mariam
Berthé, Alima
Traoré, Hadizatou Coulibaly
Koïta, Anta
Koné, Niaboula
N'Diaye, Clémentine
Coulibaly, Safiatou Touré
Traoré, Mamadou
Traoré, Naïchata
Charurat, Man
Ajayi, Samuel
Dapiap, Stephen
Otu,
Igbinoba, Festus
Benson, Okwara
Adebamowo, Clément
James, Jesse
Obaseki,
Osakede, Philip
Olasode, John
Sow, Papa Salif
Diop, Bernard
Manga, Noël Magloire
Tine, Judicael Malick
Signate Sy, Haby
Ba, Abou
Diagne, Aida
Dior, Hélène
Faye, Malick
Gueye, Ramatoulaye Diagne
Mbaye, Aminata Diack
Patassi, Akessiwe
Kotosso, Awèrou
Kariyare, Benjamin Goilibe
Gbadamassi, Gafarou
Komi, Agbo
Mensah-Zukong, Kankoé Edem
Pakpame, Pinuwe
Lawson-Evi, Annette Koko
Atakouma, Yawo
Takassi, Elom
Djeha, Améyo
Ephoévi-gah, Ayoko
Djibril, Sherifa El-Hadj
Dabis, François
Bissagnene, Emmanuel
Arrivé, Elise
Coffie, Patrick
Ekouevi, Didier
Jaquet, Antoine
Leroy, Valériane
Lewden, Charlotte
Sasco, Annie
Azani, Jean-Claude
Allou, Gérard
Balestre, Eric
Bohossou, Franck
Karcher, Sophie
Gonsan, Jules Mahan
Carrou, Jérôme Le
Lenaud, Séverin
Nchot, Célestin
Malateste, Karen
Yao, Amon Roseamonde
Siloué, Bertine
Clouet, Gwenaelle
Djetouan, Hugues
Doring, Alexandra
Kouakou, Adrienne
Rabourdin, Elodie
Rivenc, Jean
Anglaret, Xavier
Ba, Boubacar
Essanin, Jean Bosco
Ciaranello, Andrea
Datté, Sébastien
Desmonde, Sophie
Diby, Jean-Serge Elvis
Gottlieb, Geoffrey S.
Horo, Apollinaire Gninlgninrin
Kangah, Serge N'zoré
Malvy, Denis
Meless, David
Mounkaila-Harouna, Aida
Ndondoki, Camille
Shiboski, Caroline
Thiébaut, Rodolphe
PAC-CI,
Abidjan,
Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
title Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
title_full Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
title_fullStr Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
title_full_unstemmed Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
title_short Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
title_sort characteristics of hiv-2 and hiv-1/hiv-2 dually seropositive adults in west africa presenting for care and antiretroviral therapy: the iedea-west africa hiv-2 cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688850/
https://www.ncbi.nlm.nih.gov/pubmed/23824279
http://dx.doi.org/10.1371/journal.pone.0066135
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AT ellofrederic characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT tanonaristophanekoffi characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT koulesergeolivier characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT anzankofficharles characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT guehicalixte characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT akaedmondaddi characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT issoufkoffiladji characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kouakoujeanclaude characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ngbechemariesylvie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT tourepety characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT avitedidivine characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kouakoukouadio characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT mohmagloire characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT yaovalerieandoble characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT folquetmadeleineamorissani characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dainguymarieevelyne characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kouakoucyrille characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT meaassandeveroniquetanoh characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT okaberetegladys characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT zobonathalie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT acquahpatrick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kokoramarieberthe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ebouatanohfrancois characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT timitekonanmarguerite characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ahoussoulucrecediecket characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT assouanjuliekebe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT samimabeaflora characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kouadioclemence characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT rennerlorna characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT gokabamenla characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT welbeckjennifer characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT sackeyadziri characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT owiafesethntiri characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT wejsechristian characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT silvazacariasjoseda characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT paulojoao characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT rodriguesamabelia characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dasilvadavid characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT medinacandida characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT olivierasoutoines characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT østergaardlars characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT laursenalex characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT sodemannmorten characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT aabypeter characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT fomsgaardanders characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT erikstrupchristian characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT eugenolsenjesper characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT maigamoussay characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT diakitefatoumatafofana characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kalleabdoulaye characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT katiledrissa characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT traorehamaralassane characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT mintadaouda characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT cissetidiani characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dembelemamadou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT doumbiamohammed characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT fombamahamadou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kayaassetousoukho characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT traoreabdoulayem characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT traorehamady characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT toureamadouabathina characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dickofatoumata characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT syllamariam characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT berthealima characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT traorehadizatoucoulibaly characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT koitaanta characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT koneniaboula characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ndiayeclementine characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT coulibalysafiatoutoure characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT traoremamadou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT traorenaichata characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT charuratman characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ajayisamuel characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dapiapstephen characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT otu characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT igbinobafestus characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT bensonokwara characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT adebamowoclement characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT jamesjesse characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT obaseki characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT osakedephilip characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT olasodejohn characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT sowpapasalif characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT diopbernard characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT manganoelmagloire characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT tinejudicaelmalick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT signatesyhaby characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT baabou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT diagneaida characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT diorhelene characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT fayemalick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT gueyeramatoulayediagne characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT mbayeaminatadiack characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT patassiakessiwe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kotossoawerou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kariyarebenjamingoilibe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT gbadamassigafarou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT komiagbo characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT mensahzukongkankoeedem characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT pakpamepinuwe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT lawsoneviannettekoko characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT atakoumayawo characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT takassielom characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT djehaameyo characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ephoevigahayoko characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT djibrilsherifaelhadj characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dabisfrancois characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT bissagneneemmanuel characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT arriveelise characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT coffiepatrick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ekouevididier characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT jaquetantoine characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT leroyvaleriane characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT lewdencharlotte characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT sascoannie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT azanijeanclaude characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT allougerard characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT balestreeric characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT bohossoufranck characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT karchersophie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT gonsanjulesmahan characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT carroujeromele characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT lenaudseverin characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT nchotcelestin characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT malatestekaren characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT yaoamonroseamonde characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT silouebertine characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT clouetgwenaelle characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT djetouanhugues characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT doringalexandra characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kouakouadrienne characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT rabourdinelodie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT rivencjean characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT anglaretxavier characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT baboubacar characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT essaninjeanbosco characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ciaranelloandrea characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dattesebastien characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT desmondesophie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT dibyjeansergeelvis characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT gottliebgeoffreys characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT horoapollinairegninlgninrin characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT kangahsergenzore characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT malvydenis characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT melessdavid characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT mounkailaharounaaida characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT ndondokicamille characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT shiboskicaroline characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT thiebautrodolphe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT pacci characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy
AT abidjan characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy