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Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study
BACKGROUND: HIV-2 is endemic in West Africa. There is a lack of evidence-based guidelines on the diagnosis, management and antiretroviral therapy (ART) for HIV-2 or HIV-1/HIV-2 dual infections. Because of these issues, we designed a West African collaborative cohort for HIV-2 infection within the fr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688850/ https://www.ncbi.nlm.nih.gov/pubmed/23824279 http://dx.doi.org/10.1371/journal.pone.0066135 |
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author | Ekouevi, Didier K. Balestre, Eric Coffie, Patrick A. Minta, Daouda Messou, Eugene Sawadogo, Adrien Minga, Albert Sow, Papa Salif Bissagnene, Emmanuel Eholie, Serge P. Gottlieb, Geoffrey S. Dabis, François Zannou, Djimon Marcel Ahouada, Carin Akakpo, Jocelyn Ahomadegbé, Christelle Bashi, Jules Gougounon-Houéto, Alice Azon-Kouanou, Angèle Houngbé, Fabien Koumakpaï, Sikiratou Alihonou, Florence d’Almeida, Marcelline Hodonou, Irvine Hounhoui, Ghislaine Sagbo, Gracien Tossa-Bagnan, Leïla Adjide, Herman Drabo, Joseph Bognounou, René Dienderé, Arnaud Traore, Eliezer Zoungrana, Lassane Zerbo, Béatrice Sawadogo, Adrien Bruno Zoungrana, Jacques Héma, Arsène Soré, Ibrahim Bado, Guillaume Tapsoba, Achille Yé, Diarra Kouéta, Fla Ouedraogo, Sylvie Ouédraogo, Rasmata Hiembo, William Gansonré, Mady Messou, Eugène Gnokoro, Joachim Charles Koné, Mamadou Kouakou, Guillaume Martial Bosse, Clarisse Amani Brou, Kouakou Assi, Achi Isidore Chenal, Henri Hawerlander, Denise Soppi, Franck Minga, Albert Abo, Yao Bomisso, Germain Eholié, Serge Paul Amego, Mensah Deborah Noelly Andavi, Viviane Diallo, Zelica Ello, Frédéric Tanon, Aristophane Koffi Koule, Serge Olivier Anzan, Koffi Charles Guehi, Calixte Aka, Edmond Addi Issouf, Koffi Ladji Kouakou, Jean-Claude N’Gbeche, Marie-Sylvie Touré, Pety Avit-Edi, Divine Kouakou, Kouadio Moh, Magloire Yao, Valérie Andoblé Folquet, Madeleine Amorissani Dainguy, Marie-Evelyne Kouakou, Cyrille Méa-Assande, Véronique Tanoh Oka-Berete, Gladys Zobo, Nathalie Acquah, Patrick Kokora, Marie-Berthe Eboua, Tanoh François Timité-Konan, Marguerite Ahoussou, Lucrèce Diecket Assouan, Julie Kebé Sami, Mabéa Flora Kouadio, Clémence Renner, Lorna Goka, Bamenla Welbeck, Jennifer Sackey, Adziri Owiafe, Seth Ntiri Wejse, Christian Silva, Zacarias José Da Paulo, Joao Rodrigues, Amabelia da Silva, David Medina, Candida Oliviera-Souto, Ines Østergaard, Lars Laursen, Alex Sodemann, Morten Aaby, Peter Fomsgaard, Anders Erikstrup, Christian Eugen-Olsen, Jesper Maïga, Moussa Y Diakité, Fatoumata Fofana Kalle, Abdoulaye Katile, Drissa Traore, Hamar Alassane Minta, Daouda Cissé, Tidiani Dembelé, Mamadou Doumbia, Mohammed Fomba, Mahamadou Kaya, Assétou Soukho Traoré, Abdoulaye M Traoré, Hamady Toure, Amadou Abathina Dicko, Fatoumata Sylla, Mariam Berthé, Alima Traoré, Hadizatou Coulibaly Koïta, Anta Koné, Niaboula N'Diaye, Clémentine Coulibaly, Safiatou Touré Traoré, Mamadou Traoré, Naïchata Charurat, Man Ajayi, Samuel Dapiap, Stephen Otu, Igbinoba, Festus Benson, Okwara Adebamowo, Clément James, Jesse Obaseki, Osakede, Philip Olasode, John Sow, Papa Salif Diop, Bernard Manga, Noël Magloire Tine, Judicael Malick Signate Sy, Haby Ba, Abou Diagne, Aida Dior, Hélène Faye, Malick Gueye, Ramatoulaye Diagne Mbaye, Aminata Diack Patassi, Akessiwe Kotosso, Awèrou Kariyare, Benjamin Goilibe Gbadamassi, Gafarou Komi, Agbo Mensah-Zukong, Kankoé Edem Pakpame, Pinuwe Lawson-Evi, Annette Koko Atakouma, Yawo Takassi, Elom Djeha, Améyo Ephoévi-gah, Ayoko Djibril, Sherifa El-Hadj Dabis, François Bissagnene, Emmanuel Arrivé, Elise Coffie, Patrick Ekouevi, Didier Jaquet, Antoine Leroy, Valériane Lewden, Charlotte Sasco, Annie Azani, Jean-Claude Allou, Gérard Balestre, Eric Bohossou, Franck Karcher, Sophie Gonsan, Jules Mahan Carrou, Jérôme Le Lenaud, Séverin Nchot, Célestin Malateste, Karen Yao, Amon Roseamonde Siloué, Bertine Clouet, Gwenaelle Djetouan, Hugues Doring, Alexandra Kouakou, Adrienne Rabourdin, Elodie Rivenc, Jean Anglaret, Xavier Ba, Boubacar Essanin, Jean Bosco Ciaranello, Andrea Datté, Sébastien Desmonde, Sophie Diby, Jean-Serge Elvis Gottlieb, Geoffrey S. Horo, Apollinaire Gninlgninrin Kangah, Serge N'zoré Malvy, Denis Meless, David Mounkaila-Harouna, Aida Ndondoki, Camille Shiboski, Caroline Thiébaut, Rodolphe PAC-CI, Abidjan, |
author_facet | Ekouevi, Didier K. Balestre, Eric Coffie, Patrick A. Minta, Daouda Messou, Eugene Sawadogo, Adrien Minga, Albert Sow, Papa Salif Bissagnene, Emmanuel Eholie, Serge P. Gottlieb, Geoffrey S. Dabis, François Zannou, Djimon Marcel Ahouada, Carin Akakpo, Jocelyn Ahomadegbé, Christelle Bashi, Jules Gougounon-Houéto, Alice Azon-Kouanou, Angèle Houngbé, Fabien Koumakpaï, Sikiratou Alihonou, Florence d’Almeida, Marcelline Hodonou, Irvine Hounhoui, Ghislaine Sagbo, Gracien Tossa-Bagnan, Leïla Adjide, Herman Drabo, Joseph Bognounou, René Dienderé, Arnaud Traore, Eliezer Zoungrana, Lassane Zerbo, Béatrice Sawadogo, Adrien Bruno Zoungrana, Jacques Héma, Arsène Soré, Ibrahim Bado, Guillaume Tapsoba, Achille Yé, Diarra Kouéta, Fla Ouedraogo, Sylvie Ouédraogo, Rasmata Hiembo, William Gansonré, Mady Messou, Eugène Gnokoro, Joachim Charles Koné, Mamadou Kouakou, Guillaume Martial Bosse, Clarisse Amani Brou, Kouakou Assi, Achi Isidore Chenal, Henri Hawerlander, Denise Soppi, Franck Minga, Albert Abo, Yao Bomisso, Germain Eholié, Serge Paul Amego, Mensah Deborah Noelly Andavi, Viviane Diallo, Zelica Ello, Frédéric Tanon, Aristophane Koffi Koule, Serge Olivier Anzan, Koffi Charles Guehi, Calixte Aka, Edmond Addi Issouf, Koffi Ladji Kouakou, Jean-Claude N’Gbeche, Marie-Sylvie Touré, Pety Avit-Edi, Divine Kouakou, Kouadio Moh, Magloire Yao, Valérie Andoblé Folquet, Madeleine Amorissani Dainguy, Marie-Evelyne Kouakou, Cyrille Méa-Assande, Véronique Tanoh Oka-Berete, Gladys Zobo, Nathalie Acquah, Patrick Kokora, Marie-Berthe Eboua, Tanoh François Timité-Konan, Marguerite Ahoussou, Lucrèce Diecket Assouan, Julie Kebé Sami, Mabéa Flora Kouadio, Clémence Renner, Lorna Goka, Bamenla Welbeck, Jennifer Sackey, Adziri Owiafe, Seth Ntiri Wejse, Christian Silva, Zacarias José Da Paulo, Joao Rodrigues, Amabelia da Silva, David Medina, Candida Oliviera-Souto, Ines Østergaard, Lars Laursen, Alex Sodemann, Morten Aaby, Peter Fomsgaard, Anders Erikstrup, Christian Eugen-Olsen, Jesper Maïga, Moussa Y Diakité, Fatoumata Fofana Kalle, Abdoulaye Katile, Drissa Traore, Hamar Alassane Minta, Daouda Cissé, Tidiani Dembelé, Mamadou Doumbia, Mohammed Fomba, Mahamadou Kaya, Assétou Soukho Traoré, Abdoulaye M Traoré, Hamady Toure, Amadou Abathina Dicko, Fatoumata Sylla, Mariam Berthé, Alima Traoré, Hadizatou Coulibaly Koïta, Anta Koné, Niaboula N'Diaye, Clémentine Coulibaly, Safiatou Touré Traoré, Mamadou Traoré, Naïchata Charurat, Man Ajayi, Samuel Dapiap, Stephen Otu, Igbinoba, Festus Benson, Okwara Adebamowo, Clément James, Jesse Obaseki, Osakede, Philip Olasode, John Sow, Papa Salif Diop, Bernard Manga, Noël Magloire Tine, Judicael Malick Signate Sy, Haby Ba, Abou Diagne, Aida Dior, Hélène Faye, Malick Gueye, Ramatoulaye Diagne Mbaye, Aminata Diack Patassi, Akessiwe Kotosso, Awèrou Kariyare, Benjamin Goilibe Gbadamassi, Gafarou Komi, Agbo Mensah-Zukong, Kankoé Edem Pakpame, Pinuwe Lawson-Evi, Annette Koko Atakouma, Yawo Takassi, Elom Djeha, Améyo Ephoévi-gah, Ayoko Djibril, Sherifa El-Hadj Dabis, François Bissagnene, Emmanuel Arrivé, Elise Coffie, Patrick Ekouevi, Didier Jaquet, Antoine Leroy, Valériane Lewden, Charlotte Sasco, Annie Azani, Jean-Claude Allou, Gérard Balestre, Eric Bohossou, Franck Karcher, Sophie Gonsan, Jules Mahan Carrou, Jérôme Le Lenaud, Séverin Nchot, Célestin Malateste, Karen Yao, Amon Roseamonde Siloué, Bertine Clouet, Gwenaelle Djetouan, Hugues Doring, Alexandra Kouakou, Adrienne Rabourdin, Elodie Rivenc, Jean Anglaret, Xavier Ba, Boubacar Essanin, Jean Bosco Ciaranello, Andrea Datté, Sébastien Desmonde, Sophie Diby, Jean-Serge Elvis Gottlieb, Geoffrey S. Horo, Apollinaire Gninlgninrin Kangah, Serge N'zoré Malvy, Denis Meless, David Mounkaila-Harouna, Aida Ndondoki, Camille Shiboski, Caroline Thiébaut, Rodolphe PAC-CI, Abidjan, |
author_sort | Ekouevi, Didier K. |
collection | PubMed |
description | BACKGROUND: HIV-2 is endemic in West Africa. There is a lack of evidence-based guidelines on the diagnosis, management and antiretroviral therapy (ART) for HIV-2 or HIV-1/HIV-2 dual infections. Because of these issues, we designed a West African collaborative cohort for HIV-2 infection within the framework of the International epidemiological Databases to Evaluate AIDS (IeDEA). METHODS: We collected data on all HIV-2 and HIV-1/HIV-2 dually seropositive patients (both ARV-naive and starting ART) and followed-up in clinical centres in the IeDEA-WA network including a total of 13 clinics in five countries: Benin, Burkina-Faso Côte d’Ivoire, Mali, and Senegal, in the West Africa region. RESULTS: Data was merged for 1,754 patients (56% female), including 1,021 HIV-2 infected patients (551 on ART) and 733 dually seropositive for both HIV-1 and HIV 2 (463 on ART). At ART initiation, the median age of HIV-2 patients was 45.3 years, IQR: (38.3–51.7) and 42.4 years, IQR (37.0–47.3) for dually seropositive patients (p = 0.048). Overall, 16.7% of HIV-2 patients on ART had an advanced clinical stage (WHO IV or CDC-C). The median CD4 count at the ART initiation is 166 cells/mm(3), IQR (83–247) among HIV-2 infected patients and 146 cells/mm(3), IQR (55–249) among dually seropositive patients. Overall, in ART-treated patients, the CD4 count increased 126 cells/mm(3) after 24 months on ART for HIV-2 patients and 169 cells/mm(3) for dually seropositive patients. Of 551 HIV-2 patients on ART, 5.8% died and 10.2% were lost to follow-up during the median time on ART of 2.4 years, IQR (0.7–4.3). CONCLUSIONS: This large multi-country study of HIV-2 and HIV-1/HIV-2 dual infection in West Africa suggests that routine clinical care is less than optimal and that management and treatment of HIV-2 could be further informed by ongoing studies and randomized clinical trials in this population. |
format | Online Article Text |
id | pubmed-3688850 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-36888502013-07-02 Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study Ekouevi, Didier K. Balestre, Eric Coffie, Patrick A. Minta, Daouda Messou, Eugene Sawadogo, Adrien Minga, Albert Sow, Papa Salif Bissagnene, Emmanuel Eholie, Serge P. Gottlieb, Geoffrey S. Dabis, François Zannou, Djimon Marcel Ahouada, Carin Akakpo, Jocelyn Ahomadegbé, Christelle Bashi, Jules Gougounon-Houéto, Alice Azon-Kouanou, Angèle Houngbé, Fabien Koumakpaï, Sikiratou Alihonou, Florence d’Almeida, Marcelline Hodonou, Irvine Hounhoui, Ghislaine Sagbo, Gracien Tossa-Bagnan, Leïla Adjide, Herman Drabo, Joseph Bognounou, René Dienderé, Arnaud Traore, Eliezer Zoungrana, Lassane Zerbo, Béatrice Sawadogo, Adrien Bruno Zoungrana, Jacques Héma, Arsène Soré, Ibrahim Bado, Guillaume Tapsoba, Achille Yé, Diarra Kouéta, Fla Ouedraogo, Sylvie Ouédraogo, Rasmata Hiembo, William Gansonré, Mady Messou, Eugène Gnokoro, Joachim Charles Koné, Mamadou Kouakou, Guillaume Martial Bosse, Clarisse Amani Brou, Kouakou Assi, Achi Isidore Chenal, Henri Hawerlander, Denise Soppi, Franck Minga, Albert Abo, Yao Bomisso, Germain Eholié, Serge Paul Amego, Mensah Deborah Noelly Andavi, Viviane Diallo, Zelica Ello, Frédéric Tanon, Aristophane Koffi Koule, Serge Olivier Anzan, Koffi Charles Guehi, Calixte Aka, Edmond Addi Issouf, Koffi Ladji Kouakou, Jean-Claude N’Gbeche, Marie-Sylvie Touré, Pety Avit-Edi, Divine Kouakou, Kouadio Moh, Magloire Yao, Valérie Andoblé Folquet, Madeleine Amorissani Dainguy, Marie-Evelyne Kouakou, Cyrille Méa-Assande, Véronique Tanoh Oka-Berete, Gladys Zobo, Nathalie Acquah, Patrick Kokora, Marie-Berthe Eboua, Tanoh François Timité-Konan, Marguerite Ahoussou, Lucrèce Diecket Assouan, Julie Kebé Sami, Mabéa Flora Kouadio, Clémence Renner, Lorna Goka, Bamenla Welbeck, Jennifer Sackey, Adziri Owiafe, Seth Ntiri Wejse, Christian Silva, Zacarias José Da Paulo, Joao Rodrigues, Amabelia da Silva, David Medina, Candida Oliviera-Souto, Ines Østergaard, Lars Laursen, Alex Sodemann, Morten Aaby, Peter Fomsgaard, Anders Erikstrup, Christian Eugen-Olsen, Jesper Maïga, Moussa Y Diakité, Fatoumata Fofana Kalle, Abdoulaye Katile, Drissa Traore, Hamar Alassane Minta, Daouda Cissé, Tidiani Dembelé, Mamadou Doumbia, Mohammed Fomba, Mahamadou Kaya, Assétou Soukho Traoré, Abdoulaye M Traoré, Hamady Toure, Amadou Abathina Dicko, Fatoumata Sylla, Mariam Berthé, Alima Traoré, Hadizatou Coulibaly Koïta, Anta Koné, Niaboula N'Diaye, Clémentine Coulibaly, Safiatou Touré Traoré, Mamadou Traoré, Naïchata Charurat, Man Ajayi, Samuel Dapiap, Stephen Otu, Igbinoba, Festus Benson, Okwara Adebamowo, Clément James, Jesse Obaseki, Osakede, Philip Olasode, John Sow, Papa Salif Diop, Bernard Manga, Noël Magloire Tine, Judicael Malick Signate Sy, Haby Ba, Abou Diagne, Aida Dior, Hélène Faye, Malick Gueye, Ramatoulaye Diagne Mbaye, Aminata Diack Patassi, Akessiwe Kotosso, Awèrou Kariyare, Benjamin Goilibe Gbadamassi, Gafarou Komi, Agbo Mensah-Zukong, Kankoé Edem Pakpame, Pinuwe Lawson-Evi, Annette Koko Atakouma, Yawo Takassi, Elom Djeha, Améyo Ephoévi-gah, Ayoko Djibril, Sherifa El-Hadj Dabis, François Bissagnene, Emmanuel Arrivé, Elise Coffie, Patrick Ekouevi, Didier Jaquet, Antoine Leroy, Valériane Lewden, Charlotte Sasco, Annie Azani, Jean-Claude Allou, Gérard Balestre, Eric Bohossou, Franck Karcher, Sophie Gonsan, Jules Mahan Carrou, Jérôme Le Lenaud, Séverin Nchot, Célestin Malateste, Karen Yao, Amon Roseamonde Siloué, Bertine Clouet, Gwenaelle Djetouan, Hugues Doring, Alexandra Kouakou, Adrienne Rabourdin, Elodie Rivenc, Jean Anglaret, Xavier Ba, Boubacar Essanin, Jean Bosco Ciaranello, Andrea Datté, Sébastien Desmonde, Sophie Diby, Jean-Serge Elvis Gottlieb, Geoffrey S. Horo, Apollinaire Gninlgninrin Kangah, Serge N'zoré Malvy, Denis Meless, David Mounkaila-Harouna, Aida Ndondoki, Camille Shiboski, Caroline Thiébaut, Rodolphe PAC-CI, Abidjan, PLoS One Research Article BACKGROUND: HIV-2 is endemic in West Africa. There is a lack of evidence-based guidelines on the diagnosis, management and antiretroviral therapy (ART) for HIV-2 or HIV-1/HIV-2 dual infections. Because of these issues, we designed a West African collaborative cohort for HIV-2 infection within the framework of the International epidemiological Databases to Evaluate AIDS (IeDEA). METHODS: We collected data on all HIV-2 and HIV-1/HIV-2 dually seropositive patients (both ARV-naive and starting ART) and followed-up in clinical centres in the IeDEA-WA network including a total of 13 clinics in five countries: Benin, Burkina-Faso Côte d’Ivoire, Mali, and Senegal, in the West Africa region. RESULTS: Data was merged for 1,754 patients (56% female), including 1,021 HIV-2 infected patients (551 on ART) and 733 dually seropositive for both HIV-1 and HIV 2 (463 on ART). At ART initiation, the median age of HIV-2 patients was 45.3 years, IQR: (38.3–51.7) and 42.4 years, IQR (37.0–47.3) for dually seropositive patients (p = 0.048). Overall, 16.7% of HIV-2 patients on ART had an advanced clinical stage (WHO IV or CDC-C). The median CD4 count at the ART initiation is 166 cells/mm(3), IQR (83–247) among HIV-2 infected patients and 146 cells/mm(3), IQR (55–249) among dually seropositive patients. Overall, in ART-treated patients, the CD4 count increased 126 cells/mm(3) after 24 months on ART for HIV-2 patients and 169 cells/mm(3) for dually seropositive patients. Of 551 HIV-2 patients on ART, 5.8% died and 10.2% were lost to follow-up during the median time on ART of 2.4 years, IQR (0.7–4.3). CONCLUSIONS: This large multi-country study of HIV-2 and HIV-1/HIV-2 dual infection in West Africa suggests that routine clinical care is less than optimal and that management and treatment of HIV-2 could be further informed by ongoing studies and randomized clinical trials in this population. Public Library of Science 2013-06-18 /pmc/articles/PMC3688850/ /pubmed/23824279 http://dx.doi.org/10.1371/journal.pone.0066135 Text en © 2013 Ekouevi et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Ekouevi, Didier K. Balestre, Eric Coffie, Patrick A. Minta, Daouda Messou, Eugene Sawadogo, Adrien Minga, Albert Sow, Papa Salif Bissagnene, Emmanuel Eholie, Serge P. Gottlieb, Geoffrey S. Dabis, François Zannou, Djimon Marcel Ahouada, Carin Akakpo, Jocelyn Ahomadegbé, Christelle Bashi, Jules Gougounon-Houéto, Alice Azon-Kouanou, Angèle Houngbé, Fabien Koumakpaï, Sikiratou Alihonou, Florence d’Almeida, Marcelline Hodonou, Irvine Hounhoui, Ghislaine Sagbo, Gracien Tossa-Bagnan, Leïla Adjide, Herman Drabo, Joseph Bognounou, René Dienderé, Arnaud Traore, Eliezer Zoungrana, Lassane Zerbo, Béatrice Sawadogo, Adrien Bruno Zoungrana, Jacques Héma, Arsène Soré, Ibrahim Bado, Guillaume Tapsoba, Achille Yé, Diarra Kouéta, Fla Ouedraogo, Sylvie Ouédraogo, Rasmata Hiembo, William Gansonré, Mady Messou, Eugène Gnokoro, Joachim Charles Koné, Mamadou Kouakou, Guillaume Martial Bosse, Clarisse Amani Brou, Kouakou Assi, Achi Isidore Chenal, Henri Hawerlander, Denise Soppi, Franck Minga, Albert Abo, Yao Bomisso, Germain Eholié, Serge Paul Amego, Mensah Deborah Noelly Andavi, Viviane Diallo, Zelica Ello, Frédéric Tanon, Aristophane Koffi Koule, Serge Olivier Anzan, Koffi Charles Guehi, Calixte Aka, Edmond Addi Issouf, Koffi Ladji Kouakou, Jean-Claude N’Gbeche, Marie-Sylvie Touré, Pety Avit-Edi, Divine Kouakou, Kouadio Moh, Magloire Yao, Valérie Andoblé Folquet, Madeleine Amorissani Dainguy, Marie-Evelyne Kouakou, Cyrille Méa-Assande, Véronique Tanoh Oka-Berete, Gladys Zobo, Nathalie Acquah, Patrick Kokora, Marie-Berthe Eboua, Tanoh François Timité-Konan, Marguerite Ahoussou, Lucrèce Diecket Assouan, Julie Kebé Sami, Mabéa Flora Kouadio, Clémence Renner, Lorna Goka, Bamenla Welbeck, Jennifer Sackey, Adziri Owiafe, Seth Ntiri Wejse, Christian Silva, Zacarias José Da Paulo, Joao Rodrigues, Amabelia da Silva, David Medina, Candida Oliviera-Souto, Ines Østergaard, Lars Laursen, Alex Sodemann, Morten Aaby, Peter Fomsgaard, Anders Erikstrup, Christian Eugen-Olsen, Jesper Maïga, Moussa Y Diakité, Fatoumata Fofana Kalle, Abdoulaye Katile, Drissa Traore, Hamar Alassane Minta, Daouda Cissé, Tidiani Dembelé, Mamadou Doumbia, Mohammed Fomba, Mahamadou Kaya, Assétou Soukho Traoré, Abdoulaye M Traoré, Hamady Toure, Amadou Abathina Dicko, Fatoumata Sylla, Mariam Berthé, Alima Traoré, Hadizatou Coulibaly Koïta, Anta Koné, Niaboula N'Diaye, Clémentine Coulibaly, Safiatou Touré Traoré, Mamadou Traoré, Naïchata Charurat, Man Ajayi, Samuel Dapiap, Stephen Otu, Igbinoba, Festus Benson, Okwara Adebamowo, Clément James, Jesse Obaseki, Osakede, Philip Olasode, John Sow, Papa Salif Diop, Bernard Manga, Noël Magloire Tine, Judicael Malick Signate Sy, Haby Ba, Abou Diagne, Aida Dior, Hélène Faye, Malick Gueye, Ramatoulaye Diagne Mbaye, Aminata Diack Patassi, Akessiwe Kotosso, Awèrou Kariyare, Benjamin Goilibe Gbadamassi, Gafarou Komi, Agbo Mensah-Zukong, Kankoé Edem Pakpame, Pinuwe Lawson-Evi, Annette Koko Atakouma, Yawo Takassi, Elom Djeha, Améyo Ephoévi-gah, Ayoko Djibril, Sherifa El-Hadj Dabis, François Bissagnene, Emmanuel Arrivé, Elise Coffie, Patrick Ekouevi, Didier Jaquet, Antoine Leroy, Valériane Lewden, Charlotte Sasco, Annie Azani, Jean-Claude Allou, Gérard Balestre, Eric Bohossou, Franck Karcher, Sophie Gonsan, Jules Mahan Carrou, Jérôme Le Lenaud, Séverin Nchot, Célestin Malateste, Karen Yao, Amon Roseamonde Siloué, Bertine Clouet, Gwenaelle Djetouan, Hugues Doring, Alexandra Kouakou, Adrienne Rabourdin, Elodie Rivenc, Jean Anglaret, Xavier Ba, Boubacar Essanin, Jean Bosco Ciaranello, Andrea Datté, Sébastien Desmonde, Sophie Diby, Jean-Serge Elvis Gottlieb, Geoffrey S. Horo, Apollinaire Gninlgninrin Kangah, Serge N'zoré Malvy, Denis Meless, David Mounkaila-Harouna, Aida Ndondoki, Camille Shiboski, Caroline Thiébaut, Rodolphe PAC-CI, Abidjan, Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study |
title | Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study |
title_full | Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study |
title_fullStr | Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study |
title_full_unstemmed | Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study |
title_short | Characteristics of HIV-2 and HIV-1/HIV-2 Dually Seropositive Adults in West Africa Presenting for Care and Antiretroviral Therapy: The IeDEA-West Africa HIV-2 Cohort Study |
title_sort | characteristics of hiv-2 and hiv-1/hiv-2 dually seropositive adults in west africa presenting for care and antiretroviral therapy: the iedea-west africa hiv-2 cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688850/ https://www.ncbi.nlm.nih.gov/pubmed/23824279 http://dx.doi.org/10.1371/journal.pone.0066135 |
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characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT traoremamadou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT traorenaichata characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT charuratman characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT ajayisamuel characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT dapiapstephen characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT otu characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT igbinobafestus characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT bensonokwara characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT adebamowoclement characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT jamesjesse characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT obaseki characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT osakedephilip characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT olasodejohn characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT sowpapasalif characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT diopbernard characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT manganoelmagloire characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT tinejudicaelmalick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT signatesyhaby characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT baabou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT diagneaida characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT diorhelene characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT fayemalick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT gueyeramatoulayediagne characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT mbayeaminatadiack characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT patassiakessiwe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT kotossoawerou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT kariyarebenjamingoilibe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT gbadamassigafarou characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT komiagbo characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT mensahzukongkankoeedem characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT pakpamepinuwe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT lawsoneviannettekoko characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT atakoumayawo characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT takassielom characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT djehaameyo characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT ephoevigahayoko characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT djibrilsherifaelhadj characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT dabisfrancois characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT bissagneneemmanuel characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT arriveelise characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT coffiepatrick characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT ekouevididier characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT jaquetantoine characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT leroyvaleriane characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT lewdencharlotte characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT sascoannie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT azanijeanclaude characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT allougerard characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT balestreeric characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT bohossoufranck characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT karchersophie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT gonsanjulesmahan characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT carroujeromele characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT lenaudseverin characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT nchotcelestin characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT malatestekaren characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT yaoamonroseamonde characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT silouebertine characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT clouetgwenaelle characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT djetouanhugues characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT doringalexandra characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT kouakouadrienne characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT rabourdinelodie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT rivencjean characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT anglaretxavier characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT baboubacar characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT essaninjeanbosco characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT ciaranelloandrea characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT dattesebastien characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT desmondesophie characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT dibyjeansergeelvis characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT gottliebgeoffreys characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT horoapollinairegninlgninrin characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT kangahsergenzore characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT malvydenis characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT melessdavid characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT mounkailaharounaaida characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT ndondokicamille characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT shiboskicaroline characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT thiebautrodolphe characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT pacci characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy AT abidjan characteristicsofhiv2andhiv1hiv2duallyseropositiveadultsinwestafricapresentingforcareandantiretroviraltherapytheiedeawestafricahiv2cohortstudy |