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Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection

HIV-1 subtype C (C-HIV) is responsible for most HIV-1 cases worldwide. Although the pathogenesis of C-HIV is thought to predominantly involve CCR5-restricted (R5) strains, we do not have a firm understanding of how frequently CXCR4-using (X4 and R5X4) variants emerge in subjects with progressive C-H...

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Detalles Bibliográficos
Autores principales: Jakobsen, Martin R., Cashin, Kieran, Roche, Michael, Sterjovski, Jasminka, Ellett, Anne, Borm, Katharina, Flynn, Jacqueline, Erikstrup, Christian, Gouillou, Maelenn, Gray, Lachlan R., Saksena, Nitin K., Wang, Bin, Purcell, Damian F. J., Kallestrup, Per, Zinyama-Gutsire, Rutendo, Gomo, Exnevia, Ullum, Henrik, Østergaard, Lars, Lee, Benhur, Ramsland, Paul A., Churchill, Melissa J., Gorry, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688867/
https://www.ncbi.nlm.nih.gov/pubmed/23824043
http://dx.doi.org/10.1371/journal.pone.0065950